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因……导致的霉菌性主-髂动脉瘤的血管内支架移植物修复术

Endovascular Stent Graft Repair for Mycotic Aorto-Iliac Aneurysm Due to .

作者信息

Jiang Jianjun, Shao Wenchong, Shen Shuohao, Li Guangzhen, Liu Yang, Ding Xiangjiu, Su Qingbo

机构信息

Department of Vascular Surgery, Qilu Hospital of Shandong University, Jinan, China.

出版信息

J Endovasc Ther. 2024 Dec;31(6):1098-1106. doi: 10.1177/15266028231155139. Epub 2023 Feb 18.

Abstract

PURPOSE

aneurysms are very rare but life-threatening, and a standard treatment approach has yet to be established. The current study aimed to assess the safety and efficacy of endovascular treatment for aneurysms.

MATERIALS AND METHODS

The clinical data of 15 aortic-iliac aneurysm patients who underwent endovascular repair at 2 hospitals from January 2012 to December 2021 were retrospectively collected and analyzed.

RESULTS

Fifteen patients (12 men and 3 women) with a mean age of 59.3 years were included. Fourteen patients (93.3%) had a history of exposure to animals (cattle and sheep). All patients had aortic or iliac pseudoaneurysms, 9 abdominal aortic aneurysms (AAAs), 4 iliac aneurysms, and 2 AAA combined with iliac aneurysms. Endovascular aneurysm repair (EVAR) was performed in all patients without conversion to open surgery. Six cases were treated for emergency surgery due to aneurysm rupture. The immediate technique success rate was 100%, with no postoperative death. Two cases had the iliac artery ruptured again after operation because of lack of antibiotic treatment and was given endovascular treatment again. Once brucellosis is diagnosed, antibiotic treatment with doxycycline and rifampicin was initiated for all the patients until 6 months after operation. All patients survived over a median follow-up period of 45 months. Follow-up computed tomography angiography showed that all stent grafts remained patent, with no endoleak.

CONCLUSION

EVAR combined with antibiotics treatment is feasible, safe, and effective for aneurysms and represents a promising treatment option for these aneurysms.

CLINICAL IMPACT

Brucella aneurysms are very rare but life-threatening, and a standard treatment approach has yet to be established. The traditional operation management strategy is surgical resection and debridement of the infected aneurysm and the surrounding tissues. However, open surgical management in these patients causes severe trauma with high surgical risks and mortality (13.3%-40%). We tried to treat Brucella aneurysms with endovascular therapy, and the technique success and survival rate of the operation reached 100%. EVAR combined with antibiotics treatment is feasible, safe, and effective for Brucella aneurysms and represents a promising treatment option for some mycotic aneurysms.

摘要

目的

动脉瘤非常罕见但危及生命,目前尚未确立标准的治疗方法。本研究旨在评估血管内治疗动脉瘤的安全性和有效性。

材料与方法

回顾性收集并分析了2012年1月至2021年12月期间在两家医院接受血管内修复的15例主-髂动脉瘤患者的临床资料。

结果

纳入15例患者(12例男性和3例女性),平均年龄59.3岁。14例患者(93.3%)有动物(牛和羊)接触史。所有患者均有主动脉或髂假性动脉瘤,其中9例为腹主动脉瘤(AAA),4例为髂动脉瘤,2例为AAA合并髂动脉瘤。所有患者均接受了血管内动脉瘤修复术(EVAR),未转为开放手术。6例因动脉瘤破裂接受急诊手术。即刻技术成功率为100%,无术后死亡。2例患者术后因未进行抗生素治疗导致髂动脉再次破裂,再次接受血管内治疗。一旦确诊布鲁氏菌病,所有患者均开始使用多西环素和利福平进行抗生素治疗,直至术后6个月。所有患者在中位随访期45个月内均存活。随访计算机断层扫描血管造影显示所有支架移植物均保持通畅,无内漏。

结论

EVAR联合抗生素治疗对动脉瘤是可行、安全且有效的,是这些动脉瘤一种有前景的治疗选择。

临床意义

布鲁氏菌动脉瘤非常罕见但危及生命,目前尚未确立标准的治疗方法。传统的手术管理策略是对感染的动脉瘤及其周围组织进行手术切除和清创。然而,这些患者的开放手术管理会造成严重创伤,手术风险和死亡率高(13.3%-40%)。我们尝试用血管内治疗方法治疗布鲁氏菌动脉瘤,手术的技术成功率和生存率达到了100%。EVAR联合抗生素治疗对布鲁氏菌动脉瘤是可行、安全且有效的,是一些真菌性动脉瘤一种有前景的治疗选择。

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