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一名儿童的特发性肝铜中毒

Idiopathic hepatic copper toxicosis in a child.

作者信息

Maggiore G, De Giacomo C, Sessa F, Burgio G R

机构信息

Clinica Pediatrica, Università di Pavia, Italy.

出版信息

J Pediatr Gastroenterol Nutr. 1987 Nov-Dec;6(6):980-3. doi: 10.1097/00005176-198711000-00028.

Abstract

A 10-year-old Italian boy with chronic liver disease and copper overload is described. Biological and histopathological findings are similar to those described in children with Indian childhood cirrhosis. This report suggests that a disease akin to Indian childhood cirrhosis but different from Wilson disease can be found in non-Indian children probably representing a new, possibly inherited, disease of copper metabolism leading to copper overload in the liver.

摘要

本文描述了一名患有慢性肝病和铜过载的10岁意大利男孩。生物学和组织病理学发现与印度儿童肝硬化患儿中所描述的相似。本报告表明,在非印度儿童中可发现一种类似于印度儿童肝硬化但不同于威尔逊病的疾病,这可能代表一种新的、可能遗传的铜代谢疾病,导致肝脏铜过载。

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