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[头颈部区域肿瘤中的血管反应]

[Vascular reaction in tumors in the area of the head and neck].

作者信息

Grevers G, Herrmann U, Heinzmann U

机构信息

Hals-Nasen-Ohrenklinik und Poliklinik der Universität München.

出版信息

Laryngol Rhinol Otol (Stuttg). 1987 Sep;66(9):474-6.

PMID:3683041
Abstract

The vascular system possesses a variety of possibilities to respond to noxious events. Particularly the "morphological reaction" can first be observed in ultrastructural changes of the endothelial cell. In the present study we report on endothelial cell reactions in various carcinomas of the head and neck (carcinoma of the auricle, carcinoma of the maxilla). It is shown that the endothelial cell develops cytoplasmatic processes projecting into the vascular lumen. Occasionally cell edemas can be observed. The use of the scanning electron microscope allows to visualize three-dimensional aspects of the excised specimen. Tumor cells, endothelial cells and erythrocytes are obviously mixed, so that a regular vascular lumen can be found within the tumor tissue only occasionally. The results are compared and discussed, basing on available references.

摘要

血管系统具有多种应对有害事件的可能性。特别是“形态学反应”首先可在内皮细胞的超微结构变化中观察到。在本研究中,我们报告了头颈部各种癌症(耳廓癌、上颌癌)中的内皮细胞反应。结果表明,内皮细胞会形成伸入血管腔的细胞质突起。偶尔还能观察到细胞水肿。使用扫描电子显微镜可以直观呈现切除标本的三维形态。肿瘤细胞、内皮细胞和红细胞明显混合在一起,以至于在肿瘤组织中只能偶尔发现规则的血管腔。我们根据现有参考文献对结果进行了比较和讨论。

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