Tran Ngocdung T, Muradian Ibrahim K, Qureshi Nazia, Singh Jimmy, Henderson Sean O
Correctional Health Services, 450 Bauchet St., Los Angeles, CA, USA.
Correctional Health Services, 450 Bauchet St., Los Angeles, CA, USA.
J Subst Use Addict Treat. 2023 Apr;147:208984. doi: 10.1016/j.josat.2023.208984. Epub 2023 Feb 20.
Opioid overdose-related morbidity and mortality is a pressing public health crisis. Successful overdose reversal through bystander administration of naloxone is well documented, but there is an absence of literature on the implementation and impact of widespread naloxone access in a correctional setting during incarceration. The objective of this study was to describe our efforts to combat opioid overdose, prevent deaths, and examine and identify opioid use and predictors of opioid use through factors including age, sex assigned at birth, and ethnicity among the incarcerated population within the Los Angeles County jail system.
We retrospectively analyzed self-reported substance use information from all newly incarcerated persons from September 2018 to December 2020 to characterize opioid use in the Los Angeles County Jail system and used multivariable logistic regression analysis to determine predictors of substance use. We analyzed data on all cases of naloxone administration by custody personnel (i.e., all correctional officers) during the same period by examining patient demographic information, hospital discharge diagnosis, and patient outcome information. To describe naloxone training and access for incarcerated persons as an overdose prevention strategy, we reviewed electronic health record data on patient health outcomes for all cases of naloxone administration by an incarcerated person.
A total of 6.4 % (11,881 of 187,528) of incarcerated persons reported opioid use. In the multivariable analysis, reported substance use was most significantly associated with any ethnicity other than Black (aOR for White =11.2; 95 % CI 10.4, 12.0, aOR for Hispanic/Latinx 3.0; 95 % CI 2.8, 3.2, aOR for All Others; 5.2 95 % CI 4.6, 5.8) and being <65 years old. Naloxone was administered by custody personnel to a total of 129 patients, where 122 (94.6 %) survived and 7 (5.4 %) died. After the deployment of naloxone in jail housing units, there were two instances of bystander naloxone administration by incarcerated persons that led to successful opioid overdose reversal and survival.
The expansion of naloxone availability to both custody personnel and incarcerated persons is an effective and warranted method to ensure timely naloxone administration and successful overdose reversal in a correctional setting.
阿片类药物过量相关的发病率和死亡率是一个紧迫的公共卫生危机。旁观者使用纳洛酮成功逆转过量用药的情况已有充分记录,但关于在监禁期间惩教场所广泛提供纳洛酮的实施情况和影响的文献却很缺乏。本研究的目的是描述我们为应对阿片类药物过量、预防死亡所做的努力,并通过年龄、出生时指定的性别和种族等因素,研究和确定洛杉矶县监狱系统内被监禁人群中的阿片类药物使用情况及阿片类药物使用的预测因素。
我们回顾性分析了2018年9月至2020年12月期间所有新入狱人员自我报告的物质使用信息,以描述洛杉矶县监狱系统中的阿片类药物使用情况,并使用多变量逻辑回归分析来确定物质使用的预测因素。我们通过检查患者人口统计学信息、医院出院诊断和患者结局信息,分析了同期监管人员(即所有惩教人员)进行纳洛酮给药的所有病例的数据。为了描述将纳洛酮培训和获取作为过量用药预防策略提供给被监禁人员的情况,我们审查了被监禁人员进行纳洛酮给药的所有病例的患者健康结局的电子健康记录数据。
共有6.4%(187,528人中的11,881人)的被监禁人员报告使用过阿片类药物。在多变量分析中,报告的物质使用与非黑人的任何种族(白人的调整后比值比 = 11.2;95%置信区间10.4, 12.0,西班牙裔/拉丁裔的调整后比值比 = 3.0;95%置信区间2.8, 3.2,其他所有人的调整后比值比 = 5.2;95%置信区间4.6, 5.8)以及年龄小于65岁最为显著相关。监管人员共对129名患者使用了纳洛酮,其中122人(94.6%)存活,7人(5.4%)死亡。在监狱牢房区部署纳洛酮后,有两例被监禁人员旁观者使用纳洛酮成功逆转阿片类药物过量并使患者存活。
向监管人员和被监禁人员扩大纳洛酮的可及性是确保在惩教场所及时使用纳洛酮并成功逆转过量用药的有效且必要的方法。