Price Alex T, Zachary Christopher J, Laugeman Eric, Maraghechi Borna, Zhu Tong, Henke Lauren E
Washington University in St. Louis School of Medicine, St. Louis, MO, 63108, USA.
Phys Imaging Radiat Oncol. 2023 Feb 3;25:100423. doi: 10.1016/j.phro.2023.100423. eCollection 2023 Jan.
Contouring during adaptive radiotherapy (ART) can be a time-consuming process. This study describes the generation of patient specific contouring regions of interest (CRoI) for evaluating the high dose fall-off in stereotactic abdominal ART. An empirical equation was derived to determine the radius of a cylindrical patient specific CRoIs. These CRoIs were applied to 60 patients and their adaptive fractions (301 unique treatment plans). Out of the 301 unique treatment plans, 284 (94%) treatment plans contained the high dose fall-off within the CRoI. There was an expected predicted average timesaving of 2.9-min-per case. Patient specific CRoIs improves the efficiency of ART.
自适应放疗（ART）过程中的轮廓勾画可能是一个耗时的过程。本研究描述了用于评估立体定向腹部ART中高剂量剂量跌落的患者特异性感兴趣轮廓区域（CRoI）的生成。推导了一个经验方程来确定圆柱形患者特异性CRoI的半径。这些CRoI应用于60例患者及其自适应分次照射（301个独特的治疗计划）。在301个独特的治疗计划中，284个（94%）治疗计划的高剂量剂量跌落包含在CRoI内。预计每例患者平均可节省2.9分钟。患者特异性CRoI提高了ART的效率。
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