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不同国家非老年科医院科室中各种衰弱诊断工具的效用差异:一项纵向研究。

Differential utility of various frailty diagnostic tools in non-geriatric hospital departments of several countries: A longitudinal study.

机构信息

Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain.

Biomedical Research Center Network for Frailty and Healthy Ageing (CIBERFES), Institute of Health Carlos III, Madrid, Spain.

出版信息

Eur J Clin Invest. 2023 Jul;53(7):e13979. doi: 10.1111/eci.13979. Epub 2023 Mar 10.

Abstract

BACKGROUND

There is limited knowledge on the performance of different frailty scales in clinical settings. We sought to evaluate in non-geriatric hospital departments the feasibility, agreement and predictive ability for adverse events after 1 year follow-up of several frailty assessment tools.

METHODS

Longitudinal study with 667 older adults recruited from five hospitals in three different countries (Spain, Italy and United Kingdom). Participants were older than 75 years attending the emergency room, cardiology and surgery departments. Frailty scales used were Frailty Phenotype (FP), FRAIL scale, Tilburg and Groningen Frailty Indicators, and Clinical Frailty Scale (CFS). Analyses included the prevalence of frailty, degree of agreement between tools, feasibility and prognostic value for hospital readmission, worsening of disability and mortality, by tool and setting.

RESULTS

Emergency Room and cardiology were the settings with the highest frailty prevalence, varying by tool between 40.4% and 67.2%; elective surgery was the one with the lowest prevalence (between 13.2% and 38.2%). The tools showed a fair to moderate agreement. FP showed the lowest feasibility, especially in urgent surgery (35.6%). FRAIL, CFS and FP predicted mortality and readmissions in several settings, but disability worsening only in cardiology.

CONCLUSIONS

Frailty is a highly frequent condition in older people attending non-geriatric hospital departments. We recommend that based upon their current feasibility and predictive ability, the FRAIL scale, CFS and FP should be preferentially used in these settings. The low concordance among the tools and differences in prevalence reported and predictive ability suggest the existence of different subtypes of frailty.

摘要

背景

关于不同虚弱量表在临床环境中的表现,我们的了解有限。我们旨在评估在非老年科医院科室中,几种虚弱评估工具在 1 年后发生不良事件的可行性、一致性和预测能力。

方法

这是一项来自西班牙、意大利和英国的五家医院的 667 名 75 岁以上的急诊科、心内科和外科患者的纵向研究。使用的虚弱量表包括虚弱表型(FP)、衰弱量表(FRAIL)、蒂尔堡和格罗宁根虚弱指标以及临床虚弱量表(CFS)。分析包括虚弱的患病率、工具间的一致性程度、可行性以及对医院再入院、残疾恶化和死亡率的预测价值,按工具和科室进行分析。

结果

急诊科和心内科的虚弱患病率最高,各工具间患病率在 40.4%至 67.2%之间变化;择期手术科的患病率最低(在 13.2%至 38.2%之间)。各工具间具有中度至中度的一致性。FP 的可行性最低,特别是在急诊手术科室(35.6%)。FRAIL、CFS 和 FP 在多个科室预测死亡率和再入院,但仅在心内科预测残疾恶化。

结论

虚弱是在非老年科医院科室就诊的老年人中非常常见的情况。我们建议,根据当前的可行性和预测能力,在这些科室中优先使用 FRAIL 量表、CFS 和 FP。工具间的低一致性以及报道的患病率和预测能力的差异表明存在不同类型的虚弱。

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