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脂肪坏死:会诊医生的难题。

Fat necrosis: A consultant's conundrum.

作者信息

Majithia Jinita, Haria Purvi, Popat Palak, Katdare Aparna, Chouhan Sonal, Gala Kunal Bharat, Kulkarni Suyash, Thakur Meenakshi

机构信息

Radiology Department, Tata Memorial Hospital, Mumbai, India.

出版信息

Front Oncol. 2023 Feb 16;12:926396. doi: 10.3389/fonc.2022.926396. eCollection 2022.

DOI:10.3389/fonc.2022.926396
PMID:36873302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9978799/
Abstract

Fat necrosis of the breast is a benign non-suppurative inflammation of the adipose tissue and often mimics breast cancers, posing a diagnostic challenge for the clinician and radiologist. It has a myriad of appearances on different imaging techniques, ranging from the pathognomic oil cyst and benign dystrophic calcifications to indeterminate focal asymmetries, architectural distortions, and masses. A combination of different modalities can assist a radiologist in reaching a logical conclusion to avoid unnecessary interventions. The aim of this review article was to provide a comprehensive literature on the various imaging appearances of fat necrosis in the breast. Although a purely benign entity, the imaging appearances on mammography, contrast-enhanced mammography, ultrasound, and magnetic resonance imaging can be quite misleading, especially in post-therapy breasts. The purpose is to provide a comprehensive and all-inclusive review on fat necrosis with a proposed algorithm allowing a systematic approach to diagnosis.

摘要

乳腺脂肪坏死是脂肪组织的一种良性非化脓性炎症,常酷似乳腺癌,给临床医生和放射科医生带来诊断挑战。在不同的成像技术上,它有各种各样的表现,从典型的油囊肿和良性营养不良性钙化到不确定的局灶性不对称、结构扭曲和肿块。不同检查方式的联合应用有助于放射科医生得出合理结论,避免不必要的干预。这篇综述文章的目的是提供关于乳腺脂肪坏死各种成像表现的全面文献。尽管它是一种纯粹的良性病变,但乳腺钼靶、对比增强乳腺钼靶、超声和磁共振成像上的表现可能会极具误导性,尤其是在接受过治疗的乳腺中。目的是对脂肪坏死进行全面且涵盖所有方面的综述,并提出一种算法,以便采用系统的方法进行诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d713/9978799/afce9f7cd58e/fonc-12-926396-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d713/9978799/8dc2e163e15c/fonc-12-926396-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d713/9978799/afce9f7cd58e/fonc-12-926396-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d713/9978799/8dc2e163e15c/fonc-12-926396-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d713/9978799/afce9f7cd58e/fonc-12-926396-g002.jpg

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本文引用的文献

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Appearance of fat necrosis on contrast-enhanced spectral mammography.对比增强光谱乳腺摄影中脂肪坏死的表现。
BMJ Case Rep. 2022 Mar 15;15(3):e246231. doi: 10.1136/bcr-2021-246231.
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Time to development and imaging features of new calcifications in the treated breast after breast-conserving therapy.保乳治疗后新钙化灶的出现时间及影像学特征。
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单穿支腹壁下深动脉和腹壁浅动脉穿支游离皮瓣中的脂肪坏死:一项前瞻性随机研究
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Case report: Atypical lipomatous tumor of the thigh in a four-year-old girl.病例报告:一名4岁女孩大腿部的非典型脂肪瘤性肿瘤。
Front Oncol. 2024 Jul 23;14:1401861. doi: 10.3389/fonc.2024.1401861. eCollection 2024.
比较乳腺 X 线摄影、超声、磁共振成像以及这些影像学方法联合应用对小(≤2cm)乳腺癌的检测灵敏度。
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Risk Factors for Fat Necrosis After Stereotactic Partial Breast Irradiation for Early-Stage Breast Cancer in a Phase 1 Clinical Trial.立体定向部分乳房照射治疗早期乳腺癌 1 期临床试验中脂肪坏死的危险因素。
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Fat necrosis in the Breast: A systematic review of clinical.乳房脂肪坏死:临床的系统评价。
Lipids Health Dis. 2019 Jun 11;18(1):139. doi: 10.1186/s12944-019-1078-4.
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Contrast-enhanced spectral mammography in the evaluation of breast suspicious calcifications: diagnostic accuracy and impact on surgical management.对比增强光谱乳腺摄影术在评估乳腺可疑钙化中的应用:诊断准确性及对手术管理的影响
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Breast imaging surveillance after curative treatment for primary non-metastasised breast cancer in non-high-risk women: a systematic review.非高危女性原发性非转移性乳腺癌根治性治疗后的乳腺影像监测:一项系统评价
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