Binghamton University (SUNY), Binghamton, New York.
J Am Acad Child Adolesc Psychiatry. 2023 Jul;62(7):726-727. doi: 10.1016/j.jaac.2023.03.001. Epub 2023 Mar 8.
Reward processing deficits play a clear role in depression and depression risk. For example, more than a decade of research has shown that individual differences in initial reward responsiveness, indexed by the reward positivity (RewP) event-related potential (ERP) component, are associated with current depression and future depression risk. Mackin and colleagues' study builds on this previous literature by asking 2 key questions: (1) Is the magnitude of the impact of RewP on prospective changes in depressive symptoms similar during late childhood and adolescence? and (2) Are prospective links between RewP and depressive symptoms transactional, with depressive symptoms also predicting future change in RewP during this developmental window? These questions are important, because this is a time period during which rates of depression increase dramatically and when there are normative changes in reward processing. However, we know very little about how relations between reward processing and depression may change across development.
奖励加工缺陷在抑郁症和抑郁风险中起着明显的作用。例如,十多年的研究表明,初始奖励反应的个体差异,由奖励正波(RewP)事件相关电位(ERP)成分来表示,与当前的抑郁症和未来的抑郁风险有关。Mackin 及其同事的研究是在前人文献的基础上进行的,提出了 2 个关键问题:(1)RewP 对儿童晚期和青少年期抑郁症状的预期变化的影响程度是否相似?(2)RewP 和抑郁症状之间的前瞻性联系是否具有相互作用性,即抑郁症状也可以预测在此发育窗口期内 RewP 的未来变化?这些问题很重要,因为这是一个抑郁发生率急剧上升的时期,也是奖励加工出现正常变化的时期。然而,我们对奖励处理和抑郁之间的关系如何随发展而变化知之甚少。