Nuclear origin of the centrifugal visual pathway in birds of prey.

The isthmo-optic nucleus (NIO) at the origin of the retinopetal pathway was examined in 12 birds of prey (strigiforms and falconiforms) using cytoarchitectonic methods and after the intraocular injection of the regrograde tracers Rhodamine beta-isothiocyanate and Fast blue. The NIO was found to be poorly differentiated and reticular in appearance and depending on the species contained between 900 and 1400 neurons. These values are approximately 10 times less than those recorded in the pigeon and chicken. As in the latter species, the experimental data obtained in the strigiform Tyto alba showed the presence of retinopetal ectopic neurons bilaterally. However the ipsilateral contingent was proportionally larger in the nocturnal raptor. The functional significance of the poorly developed centrifugal visual system in birds of prey is discussed.