Glinskiĭ G V, Vinnitskiĭ V B
Eksp Onkol. 1987;9(5):78-80.
The conjugate of amino acids and glucosamine (glycamine) was purified to homogeneity from blood plasma of rats with Guerin carcinoma. The NH2-groups of amino acids in the glycamine are free. Amino acids are linked to glucosamine via carboxyl groups. 8 amino acids residues were identified in the glycamine molecule (Glu-2, Ser-2, Gly-3, Lys-1). Spatial atomic-molecular model of the glycamine molecule was developed. Two glucosamine molecules are linked to diaminosaccharide via (1-4)-bond, 8 amino acid molecules are linked to diaminosaccharide via 6 ester and 2 pseudopeptide bonds.
从患格林癌大鼠的血浆中纯化出氨基酸与氨基葡萄糖(糖胺)的结合物,使其达到同质。糖胺中氨基酸的氨基是游离的。氨基酸通过羧基与氨基葡萄糖相连。在糖胺分子中鉴定出8个氨基酸残基(谷氨酸-2、丝氨酸-2、甘氨酸-3、赖氨酸-1)。构建了糖胺分子的空间原子-分子模型。两个氨基葡萄糖分子通过(1-4)键与二氨基糖相连,8个氨基酸分子通过6个酯键和2个假肽键与二氨基糖相连。