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《儿童新型冠状病毒感染相关咳嗽诊断与治疗专家共识》

[Expert consensus on diagnosis and treatment of COVID-19 infection related cough in children].

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Mar 6;57(3):309-317. doi: 10.3760/cma.j.cn112150-20230120-00052.

Abstract

An epidemic outbreak of the corona virus disease 2019(COVID-19) Omicron variant occurred in most regions of China. Children are susceptible to COVID-19 and the vast majority of them suffer from upper respiratory tract infection. Cough is one of the most common symptoms. COVID-19 infection related cough includes acute cough, persistent cough and chronic cough, and children with original chronic cough or chronic lung disease can also induce or aggravate symptom of cough after infection, which has a great impact on children's physical and mental health. The treatment for COVID-19 infection related cough vary with the etiology. Improper treatment would delay the patient's condition and increase adverse drug reaction. Currently, there is no guideline or consensus on the diagnosis and treatment of COVID-19 infection related cough in children in China, therefore this consensus is drafted. Referring to the latest international research and the diagnostic and therapeutic strategy for COVID-19 infection (Tenth Edition For Trial Implementation), and combining with clinical diagnosis and treatment experience,the consensus elaborates the pathogenesis and etiology of COVID-19 infection related cough, the use of cough relievers and expectorants, as well as the key points of diagnosis and treatment of different etiological factors. It is expected to provide specific and feasible guidance scheme for pediatricians, general practitioners and clinical pharmacists.

摘要

2019年冠状病毒病(COVID-19)奥密克戎变异株疫情在中国大部分地区爆发。儿童易感染COVID-19,其中绝大多数患有上呼吸道感染。咳嗽是最常见的症状之一。COVID-19感染相关咳嗽包括急性咳嗽、持续性咳嗽和慢性咳嗽,原有慢性咳嗽或慢性肺病的儿童感染后也可诱发或加重咳嗽症状,对儿童身心健康有很大影响。COVID-19感染相关咳嗽的治疗因病因不同而异。治疗不当会延误病情并增加药物不良反应。目前,我国尚无关于儿童COVID-19感染相关咳嗽诊断和治疗的指南或共识,因此起草本共识。参考最新国际研究及COVID-19感染诊疗方案(试行第十版),并结合临床诊疗经验,本共识阐述了COVID-19感染相关咳嗽的发病机制和病因、镇咳祛痰药的使用以及不同病因的诊断和治疗要点。期望为儿科医生、全科医生和临床药师提供具体可行的指导方案。

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