放射性碘治疗甲状腺乳头状癌后 131I 碘在鼻泪囊/管中的蓄积。
Accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer.
机构信息
Department of Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
出版信息
J Pak Med Assoc. 2023 Mar;73(3):713-714. doi: 10.47391/JPMA.23-22.
SPECT/CT is a powerful tool for assessing unexpected concentrations of radioiodine resulting from benign uptake in organs with sodium-iodide symporter (NIS) expression. We report a case of accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer. A whole-body scan was taken 3 days after the administration of 5.5 GBq of 131Iodine. SPECT/CT images localized the focal tracer uptake in the nasolacrimal sac/duct likely due to nasolacrimal duct obstruction secondary to prior radioiodine or iodine therapies. Hybrid SPECT/CT allows precise anatomical localization and help differentiate benign mimics of disease, which can alter patient management.
SPECT/CT 是评估因钠-碘转运体（NIS）表达而导致的良性摄取导致的意外放射性碘浓度的有力工具。我们报告了一例甲状腺乳头状癌放射性碘治疗后泪囊/管内 131I 蓄积的病例。在给予 5.5GBq 131I 后 3 天进行全身扫描。SPECT/CT 图像定位了泪囊/管中局灶性示踪剂摄取，可能是由于先前的放射性碘或碘治疗引起的鼻泪管阻塞所致。混合 SPECT/CT 可实现精确的解剖定位，并有助于区分良性疾病模拟物，这可能会改变患者的管理。
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