Departments of Dermatology, College of Medicine, Shaqra University, Dawadmi, Saudi Arabia.
Departments of Dermatology, College of Medicine, Shaqra University, Dawadmi, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2023 Jun;42:103510. doi: 10.1016/j.pdpdt.2023.103510. Epub 2023 Mar 20.
Vitamin D (VD) insufficiency has been linked to a number of autoimmune illnesses including, alopecia areata (AA). To distinguish between clinically common hair problems, trichoscopy is a beneficial non-invasive, rapid, and affordable procedure that is yet neglected.
to evaluate trichoscopic patterns and severity in various clinical categories of AA considering vitamin D level (VDL). Also, focusing on specific patterns of trichoscopy in AA related to VDL.
Severity of Alopecia Tool (SALT) was used to clinically assess patients with AA scores. Trichoscopic patterns were analyzed concerning VDL and disease severity. The VDL was estimated for 59 patients and 60 healthy controls.
VDL was higher in healthy controls than in AA patients. The most common trichoscopic findings seen in our study were yellow dots (77.97%), followed by black dots (67.8%), and broken hairs (59.32%). Short vellus hairs and yellow dots were the most common in remitting AA. In progressive AA, the most common findings were broken hairs, yellow dots, and tapering hairs. VDL was significantly higher in both mild and moderate AA.
VDL was significantly lower in severe AA and active progressive disease. Trichoscopic features could predict disease activity and VDL in patients with AA. Broken and tapering hairs will be more represented in patients with progressive disease. Short vellus hairs were seen more in stable or remitting disease. Furthermore, black dots and broken hairs were more prevalent in AA with deficient VDL.
维生素 D(VD)不足与许多自身免疫性疾病有关,包括斑秃(AA)。为了区分临床上常见的毛发问题,毛发镜检查是一种有益的、非侵入性的、快速的、负担得起的程序,但尚未得到重视。
评估不同临床类别 AA 的毛发镜检查模式和严重程度,同时考虑维生素 D 水平(VDL)。此外,还关注与 VDL 相关的 AA 的特定毛发镜检查模式。
使用脱发严重程度评估工具(SALT)对 AA 患者进行临床评估。根据 VDL 和疾病严重程度分析毛发镜检查模式。对 59 名患者和 60 名健康对照者进行了 VDL 估计。
健康对照组的 VDL 高于 AA 患者。我们研究中最常见的毛发镜检查发现是黄色小点(77.97%),其次是黑色小点(67.8%)和断发(59.32%)。在缓解性 AA 中,最常见的发现是短毳毛和黄色小点。在进行性 AA 中,最常见的发现是断发、黄色小点和锥形发。轻度和中度 AA 中 VDL 明显升高。
严重 AA 和活动进展性疾病的 VDL 明显降低。毛发镜检查特征可预测 AA 患者的疾病活动度和 VDL。进行性疾病患者中更会出现断发和锥形发。稳定或缓解性疾病中更常见短毳毛。此外,黑色小点和断发在 VDL 缺乏的 AA 中更为常见。