Aden Durre, Zaheer Sufian, Saxena Divita, Ranga Sunil
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
J Midlife Health. 2022 Jul-Sep;13(3):257-259. doi: 10.4103/jmh.jmh_17_22. Epub 2023 Jan 14.
Primary pleomorphic liposarcoma of the breast is a very rare mesenchymal tumor. Sarcoma arising in the breast constitutes <1% of all malignant breast tumors, and liposarcoma of the breast has an incidence of 0.3% of all mammary sarcomas. It is a very aggressive tumor with a high incidence of recurrences and distant metastasis. They can mimic primary invasive breast cancer clinically as well as radiologically. Histology and radiological evaluation of the patient help correctly type and grade this malignancy. On microscopy, the tumor is composed of pleomorphic tumor cells with atypical lipoblast with areas of necrosis and mitosis. We report one such rare case here.
原发性乳腺多形性脂肪肉瘤是一种非常罕见的间叶组织肿瘤。乳腺发生的肉瘤占所有恶性乳腺肿瘤的比例不到1%,而乳腺脂肪肉瘤的发病率占所有乳腺肉瘤的0.3%。它是一种侵袭性很强的肿瘤,复发率和远处转移率都很高。在临床和放射学上,它们可能会模仿原发性浸润性乳腺癌。对患者进行组织学和放射学评估有助于正确地对这种恶性肿瘤进行分型和分级。在显微镜下,肿瘤由具有非典型脂肪母细胞的多形性肿瘤细胞组成,并伴有坏死和有丝分裂区域。我们在此报告这样一例罕见病例。