Department of Neurosurgery, University Medical Center Mainz, Mainz, Germany.
Department of Neurosurgery and Neurooncology, First Faculty of Medicine, Charles University and Military Hospital, Prague, Czech Republic.
Exp Clin Endocrinol Diabetes. 2023 Jun;131(6):362-366. doi: 10.1055/a-2061-1284. Epub 2023 Mar 23.
Surgery is, next to medical and radiation therapy, the mainstay therapy for pituitary adenomas. While scientific consensus regarding the key aspects of pituitary surgery exists among neurosurgeons, procedures are not standardized and might vary significantly between hospitals and surgeons.
To provide an overview of how neurosurgical departments in Germany manage pituitary surgery.
Responses from the European Pituitary Adenoma Surgery Survey were analyzed. The survey contained 60 questions regarding demographics, training, surgical and endocrinological aspects, and patient management.
Sixty neurosurgical centers from Germany responded to the survey. Among the centers, 35.3% (n=18) exclusively use the microscopic and 31.1% (n=14) the endoscopic technique; all other centers (n=28) use both approaches. Of responding centers, 20% (n=12) perform less than 10 transsphenoidal pituitary surgeries per year, and 1.7% (n=1), more than 100 operations. The number of transcranial pituitary operations is significantly smaller, with 53.3% of centers performing only 0-2 per year, 35% performing 3-5, and only one center (1.7%) performing more than 15 transcranial operations per year. In 8 centers (13.3%), surgeries are always performed together with an ENT surgeon; in 29 centers (48.4%) ENT surgeons are never involved. In most centers (n=54, 90%) intraoperative MRI is not available. Image guidance (with preoperative CT and/or MRI data) is used by 91.7% of respondents (n=55). Forty-two centers (72.4%) routinely prescribe hydrocortisone after pituitary surgery, and 75% (n=45) have pituitary board meetings with endocrinologists, radiologists, and radiosurgeons. Fifty-two (86.7%) respondents perform the first follow-up scan by MRI 3-4 months after surgery.
The data showed differences as well as similarities between centers and could help to discuss the standardization of methods and the formation of networks and certification to improve patient care.
手术是除了医学和放射治疗之外,治疗垂体腺瘤的主要方法。虽然神经外科医生对垂体手术的关键方面有科学共识,但手术方法并未标准化,并且不同医院和外科医生之间可能存在显著差异。
提供德国神经外科部门管理垂体手术的概述。
分析欧洲垂体腺瘤手术调查的回复。该调查包含 60 个关于人口统计学、培训、手术和内分泌方面以及患者管理的问题。
德国的 60 个神经外科中心对调查做出了回应。在这些中心中,35.3%(n=18)仅使用显微镜技术,31.1%(n=14)仅使用内镜技术;所有其他中心(n=28)都使用这两种方法。在做出回应的中心中,20%(n=12)每年进行的经蝶窦垂体手术少于 10 例,1.7%(n=1)每年进行超过 100 例手术。经颅垂体手术的数量要小得多,其中 53.3%的中心每年仅进行 0-2 例,35%的中心每年进行 3-5 例,只有一个中心(1.7%)每年进行超过 15 例经颅手术。在 8 个中心(13.3%)中,手术总是与耳鼻喉科医生一起进行;在 29 个中心(48.4%)中,耳鼻喉科医生从不参与。在大多数中心(n=54,90%)中,术中 MRI 不可用。有 91.7%的受访者(n=55)使用图像引导(使用术前 CT 和/或 MRI 数据)。42 个中心(72.4%)常规在垂体手术后开 hydrocortisone,75%(n=45)有垂体委员会会议,邀请内分泌学家、放射科医生和放射外科医生参加。52 个(86.7%)受访者在手术后 3-4 个月通过 MRI 进行第一次随访扫描。
数据显示了中心之间的差异和相似之处,并有助于讨论方法的标准化以及网络和认证的形成,以改善患者的护理。