含氟嘧啶类药物研发的历程：藤井哲郎教授的成就纪事
Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.
作者信息
Maehara Yoshihiko, Oki Eiji, Ota Mitsuhiko, Harimoto Norifumi, Ando Koji, Nakanishi Ryota, Kawazoe Tetsuro, Fujimoto Yoshiaki, Nonaka Kentaro, Kitao Hiroyuki, Iimori Makoto, Makino Kunio, Takechi Teiji, Sagara Takeshi, Miyadera Kazutaka, Matsuoka Kazuaki, Tsukihara Hiroshi, Kataoka Yuki, Wakasa Takeshi, Ochiiwa Hiroaki, Kamahori Yoshihiro, Tokunaga Eriko, Saeki Hiroshi, Yoshizumi Tomoharu, Kakeji Yoshihiro, Shirabe Ken, Baba Hideo, Shimada Mitsuo
机构信息
Kyushu Central Hospital of the Mutual Aid Association of Public School Teachers, Fukuoka, 815-8588, Japan.
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
出版信息
Int J Clin Oncol. 2023 May;28(5):613-624. doi: 10.1007/s10147-023-02326-w. Epub 2023 Mar 24.
Prof. Setsuro Fujii achieved significant results in the field of drug discovery research in Japan. He developed nine well-known drugs: FT, UFT, S-1 and FTD/TPI are anticancer drugs, while cetraxate hydrochloride, camostat mesilate, nafamostat mesilate, gabexate mesilate and pravastatin sodium are therapeutic drugs for various other diseases. He delivered hope to patients with various diseases across the world to improve their condition. Even now, drug discovery research based on Dr. Fujii's ideas is continuing.
藤井哲郎教授在日本的药物研发研究领域取得了显著成果。他研发了九种知名药物：FT、UFT、S-1和FTD/TPI是抗癌药物，而盐酸西曲酸酯、甲磺酸卡莫司他、甲磺酸萘莫司他、甲磺酸加贝酯和普伐他汀钠是用于治疗其他各种疾病的药物。他为世界各地患有各种疾病的患者带来了改善病情的希望。即使在现在，基于藤井博士理念的药物研发研究仍在继续。
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