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埃塞俄比亚西北部巴赫达尔慢性门诊医疗患者的多重疾病与健康相关生活质量:部分比例优势模型的应用

Multimorbidity and health-related quality of life among patients attending chronic outpatient medical care in Bahir Dar, Northwest Ethiopia: The application of partial proportional odds model.

作者信息

Eyowas Fantu Abebe, Schneider Marguerite, Balcha Shitaye Alemu, Pati Sanghamitra, Getahun Fentie Ambaw

机构信息

School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health University of Cape Town, Cape Town, South Africa.

出版信息

PLOS Glob Public Health. 2022 Nov 2;2(11):e0001176. doi: 10.1371/journal.pgph.0001176. eCollection 2022.

Abstract

BACKGROUND

Multimorbidity, the presence of two or more chronic non-communicable diseases (NCDs) in a given person affects all aspects of people's lives. Poor quality of life (QoL) is one of the major consequences of living with multimorbidity. Although healthcare should support multimorbid individuals to achieve a better quality of life, little is known about the effect of multimorbidity on the QoL of patients living with chronic conditions. This study aimed to determine the influence of multimorbidity on QoL among clients attending chronic outpatient medical care in Bahir Dar, Northwest Ethiopia.

METHODOLOGY

A multi-centered facility-based study was conducted among 1440 participants aged 40+ years. Two complementary methods were employed to collect sociodemographic and disease related data. We used the short form (SF-12 V2) instrument to measure quality of life (QoL). The data were analyzed by STATA V.16, and a multivariate partial proportional odds model was fitted to identify covariates associated with quality of life. Statistical significance was considered at p-value <0.05.

PRINCIPAL FINDINGS

Multimorbidity was identified in 54.8% (95% CI = 52.2%-57.4%) of the sample. A significant proportion (33.5%) of the study participants had poor QoL and a quarter (25.8%) of them had moderate QoL. Advanced age, obesity and living with multimorbidity were the factors associated with poor QoL. Conversely, perceived social support and satisfaction with care were the variables positively associated with better QoL.

CONCLUSION

The magnitude of multimorbidity in this study was high and individuals living with multimorbidity had a relatively poorer QoL than those without multimorbidity. Care of people with chronic multiple conditions has to be oriented to the realities of multimorbidity burden and its implication on QoL. It is also imperative to replicate the methods we employed to measure and analyze QoL data in this study for facilitating comparison and further development of the approaches.

摘要

背景

多病共存,即一个人患有两种或更多慢性非传染性疾病(NCDs),会影响人们生活的方方面面。生活质量低下是多病共存的主要后果之一。尽管医疗保健应支持患有多种疾病的个体实现更高的生活质量,但对于多病共存对慢性病患者生活质量的影响知之甚少。本研究旨在确定多病共存对埃塞俄比亚西北部巴赫达尔接受慢性门诊医疗的患者生活质量的影响。

方法

对1440名40岁及以上的参与者进行了一项多中心的基于机构的研究。采用两种互补方法收集社会人口统计学和疾病相关数据。我们使用简表(SF-12 V2)工具来测量生活质量(QoL)。数据由STATA V.16进行分析,并拟合多元部分比例优势模型以识别与生活质量相关的协变量。p值<0.05时被认为具有统计学意义。

主要发现

样本中54.8%(95%CI = 52.2%-57.4%)的人存在多病共存情况。相当比例(33.5%)的研究参与者生活质量较差,其中四分之一(25.8%)的人生活质量中等。高龄、肥胖和多病共存是与生活质量差相关的因素。相反,感知到的社会支持和对护理的满意度是与更好的生活质量呈正相关的变量。

结论

本研究中多病共存的比例很高,与没有多病共存的人相比,患有多种疾病的个体生活质量相对较差。对患有多种慢性疾病的人的护理必须针对多病共存负担的现实及其对生活质量的影响。同样有必要重复我们在本研究中用于测量和分析生活质量数据的方法,以促进比较和方法的进一步发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0673/10021695/afb37f2afa9f/pgph.0001176.g001.jpg

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