Beilin L J, Armstrong B K, Margetts B M, Rouse I L, Vandongen R
University Department of Medicine, Royal Perth Hospital, Australia.
Nephron. 1987;47 Suppl 1:37-41. doi: 10.1159/000184551.
There is now convincing evidence from epidemiological studies and randomized controlled trials that adoption of an ovo-lacto vegetarian diet leads to blood pressure reduction in both normotensive and hypertensive subjects. This effect appears to be independent of both dietary sodium and weight loss but additive to effects of weight reduction. Long-term adherence to a vegetarian diet is associated with less of a rise of blood pressure with age and a decreased prevalence of hypertension. The nutrients responsible for these effects have not been clearly identified and the mechanisms involved are unknown. Resolution of these questions is needed to enable more widespread adoption of dietary changes which may reduce the prevalence of hypertension, reduce antihypertensive drug dependence and by effects on blood pressure and blood lipids ameliorate the natural history of hypertensive cardiovascular disease.
目前，流行病学研究和随机对照试验提供了令人信服的证据，表明采用蛋奶素食饮食可使血压正常者和高血压患者的血压降低。这种效果似乎与饮食中的钠和体重减轻无关，但与体重减轻的效果相加。长期坚持素食与随着年龄增长血压升高幅度较小以及高血压患病率降低有关。导致这些效果的营养素尚未明确确定，其涉及的机制也不清楚。需要解决这些问题，以便能够更广泛地采用饮食改变措施，这可能会降低高血压的患病率，减少对抗高血压药物的依赖，并通过对血压和血脂的影响改善高血压心血管疾病的自然病程。
