经颅直流电刺激对侧刺激增强偏瘫型脑瘫青少年双侧皮质脊髓束兴奋性：简短报告
Anodal Contralesional tDCS Enhances CST Excitability Bilaterally in an Adolescent with Hemiparetic Cerebral Palsy: A Brief Report.
机构信息
Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, USA.
出版信息
Dev Neurorehabil. 2023 Apr;26(3):216-221. doi: 10.1080/17518423.2023.2193626. Epub 2023 Mar 26.
Hemiparetic cerebral palsy (HCP), weakness on one side of the body typically caused by perinatal stroke, is characterized by lifelong motor impairments related to alterations in the corticospinal tract (CST). CST reorganization could be a useful biomarker to guide applications of neuromodulatory interventions, such as transcranial direct current stimulation (tDCS), to improve the effectiveness of rehabilitation therapies. We evaluated an adolescent with HCP and CST reorganization who demonstrated persistent heightened CST excitability in both upper limbs following anodal contralesional tDCS. The results support further investigation of targeted tDCS as an adjuvant therapy to traditional neurorehabilitation for upper limb function.
偏瘫型脑瘫（hemiparetic cerebral palsy，HCP）是一种由围产期中风引起的身体单侧无力，其特征是终生与皮质脊髓束（corticospinal tract，CST）改变相关的运动障碍。CST 重组可能是一种有用的生物标志物，可指导神经调节干预措施（如经颅直流电刺激（transcranial direct current stimulation，tDCS））的应用，以提高康复治疗的效果。我们评估了一名 HCP 患者，其 CST 发生重组，在对侧经颅直流电刺激（anodal contralesional tDCS）后，其双侧上肢 CST 兴奋性持续升高。结果支持进一步研究靶向 tDCS 作为传统神经康复的辅助治疗，以改善上肢功能。
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