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新冠疫情对输血用血的影响:来自韩国一家三级中心的两年经验

Impact of the COVID-19 Pandemic on the Usage of Blood for Transfusions: A 2-Year Experience from a Tertiary Center in Korea.

作者信息

Roh Juhye, Lee Jangwook, Park Jinyoung, Kang Hee Jung, Lee Young Kyung, Kim Han-Sung, Cho Yonggeun

机构信息

Department of Laboratory Medicine, Hallym University Sacred Heart Hospital, Anyang 14068, Republic of Korea.

Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang 10326, Republic of Korea.

出版信息

Vaccines (Basel). 2023 Mar 3;11(3):585. doi: 10.3390/vaccines11030585.

Abstract

The coronavirus disease (COVID-19) outbreak affected the utilization and management of blood products in hospitals. Blood shortages occurred owing to social distancing policies and reduction in blood donors. However, only a few studies examined whether these changes affected blood usage and transfusion patterns. We retrospectively reviewed blood component usage according to hospital departments and phases of surgery in transfused patients admitted between 1 March 2019 and 28 February 2021, in a single center in Anyang, Korea. We also analyzed the length of hospital stay and mortality to determine prognosis. In 2020, 32,050 blood components were transfused to 2877 patients, corresponding to 15.8% and 11.8% less than the rates in 2019, respectively. Postoperative usage of blood products significantly decreased in 2020 (3.87 ± 6.50) compared to 2019 (7.12 ± 21.71) ( = 0.047). The length of hospital stay of the patients who underwent postoperative transfusion in 2019 ( = 197) was 13.97 ± 11.95 days, which was not significantly different from that in 2020 ( = 167), i.e., 16.44 ± 17.90 days ( = 0.118). Further, 9 of 197 postoperative transfusion patients died in 2019, while 8 of 167 patients died in 2020 ( = 0.920). The COVID-19 pandemic resulted in limited blood supply and reduced postoperative transfusions; however, patient prognosis was not affected.

摘要

冠状病毒病(COVID-19)疫情影响了医院血液制品的使用和管理。由于社交距离政策和献血者减少,出现了血液短缺的情况。然而,只有少数研究调查了这些变化是否影响了血液使用和输血模式。我们回顾性分析了2019年3月1日至2021年2月28日期间在韩国安阳的一个单一中心收治的输血患者的血液成分使用情况,这些患者根据医院科室和手术阶段进行分类。我们还分析了住院时间和死亡率以确定预后情况。2020年,共向2877名患者输注了32050个血液成分,分别比2019年的输注率低15.8%和11.8%。与2019年(7.12±21.71)相比,2020年血液制品的术后使用量显著下降(3.87±6.50)(P = 0.047)。2019年接受术后输血的患者(n = 197)的住院时间为13.97±11.95天,与2020年(n = 167)的住院时间(16.44±17.90天)相比无显著差异(P = 0.118)。此外,197名术后输血患者中有9人在2019年死亡,而167名患者中有8人在2020年死亡(P = 0.920)。COVID-19大流行导致血液供应受限和术后输血减少;然而,患者的预后并未受到影响。

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