与非工作时间住院相关的死亡率和再入院差异:澳大利亚昆士兰州的一项基于人群的队列研究。

Mortality and readmission differences associated with after-hours hospital admission: A population-based cohort study in Queensland Australia.

作者信息

Bell Anthony, Boyle Justin, Rolls David, Khanna Sankalp, Good Norm, Xie Yang, Romeo Michele

机构信息

Queensland Department of Health now at Rockingham General Hospital Perth Australia.

CSIRO Brisbane Australia.

出版信息

Health Sci Rep. 2023 Mar 27;6(3):e1150. doi: 10.1002/hsr2.1150. eCollection 2023 Mar.

Abstract

BACKGROUND AND AIMS

Policy makers and health system managers are seeking evidence on the risks involved for patients associated with after-hours care. This study of approximately 1 million patients who were admitted to the 25 largest public hospitals in Queensland Australia sought to quantify mortality and readmission differences associated with after-hours hospital admission.

METHODS

Logistic regression was used to assess whether there were any differences in mortality and readmissions based on the time inpatients were admitted to hospital (after-hours versus within hours). Patient and staffing data, including the variation in physician and nursing staff numbers and seniority were included as explicit predictors within patient outcome models.

RESULTS

After adjusting for case-mix confounding, statistically significant higher mortality was observed for patients admitted on weekends via the hospital's emergency department compared to within hours. This finding of elevated mortality risk after-hours held true in sensitivity analyses which explored broader definitions of after-hours care: an "Extended" definition comprising a weekend extending into Friday night and early Monday morning; and a "Twilight" definition comprising weekends and weeknights.There were no significant differences in 30-day readmissions for emergency or elective patients admitted after-hours. Increased mortality risks for elective patients was found to be an evening/weekend effect rather than a day-of-week effect. Workforce metrics that played a role in observed outcome differences within hours/after-hours were more a time of day rather than day of week effect, i.e. staffing impacts differ more between day and night than the weekday versus weekend.

CONCLUSION

Patients admitted after-hours have significantly higher mortality than patients admitted within hours. This study confirms an association between mortality differences and the time patients were admitted to hospital, and identifies characteristics of patients and staffing that affect those outcomes.

摘要

背景与目的

政策制定者和卫生系统管理者正在寻找与非工作时间医疗相关的患者风险证据。这项对澳大利亚昆士兰州25家最大公立医院近100万名入院患者的研究,旨在量化与非工作时间入院相关的死亡率和再入院差异。

方法

采用逻辑回归分析,评估根据患者入院时间(非工作时间与工作时间内)在死亡率和再入院率方面是否存在差异。患者和人员配备数据,包括医生和护士人数及资历的差异,被纳入患者结局模型作为明确的预测因素。

结果

在调整病例组合混杂因素后,与工作时间内入院的患者相比,周末通过医院急诊科入院的患者死亡率在统计学上显著更高。在探索非工作时间医疗更广泛定义的敏感性分析中,非工作时间死亡率升高这一发现依然成立:“扩展”定义包括延伸至周五晚上和周一清晨的周末;“黄昏”定义包括周末和工作日夜晚。非工作时间入院的急诊或择期患者30天再入院率无显著差异。发现择期患者死亡率增加是傍晚/周末效应而非星期效应。在工作时间内/非工作时间观察到的结局差异中起作用的劳动力指标更多是一天中的时间而非星期效应,即人员配备影响在白天和夜晚之间的差异大于工作日与周末之间的差异。

结论

非工作时间入院的患者死亡率显著高于工作时间内入院的患者。本研究证实了死亡率差异与患者入院时间之间的关联,并确定了影响这些结局的患者和人员配备特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2a1/10041863/ff58e3fc9a85/HSR2-6-e1150-g001.jpg

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