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在一所公立三级大学医院提高糖尿病患者疫苗接种覆盖率的策略:一项随机对照试验。

Strategy to increase vaccination coverage in diabetic patients at a public tertiary university hospital: A randomized controlled trial.

作者信息

Guerra Giulia Limana, Pedro Fabio Lopes, Severo Mateus Dornelles, Guerra Giorgia Limana, Ribeiro Tiango Aguiar

机构信息

Postgraduate Program of Health Science, Federal University of Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.

Endocrinology Department, University Hospital of Santa Maria (HUSM), Federal University of Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.

出版信息

SAGE Open Med. 2023 Mar 24;11:20503121231161193. doi: 10.1177/20503121231161193. eCollection 2023.

Abstract

OBJECTIVE

To evaluate whether there is an increase in vaccination rates of patients with diabetes mellitus who received guidance to update their vaccination schedules for influenza, hepatitis B, pneumonia, and tetanus.

METHODOLOGY

A randomized controlled trial was conducted between December 2018 and November 2020. The sample consisted of 139 patients from the endocrinology service outpatient clinic of Santa Maria University Hospital was randomized into an intervention group ( = 68) and a control group ( = 71). The intervention consisted of a phone call to update the vaccination schedule for the diseases evaluated.

RESULTS

The mean age of the subjects was 59.17 ± 12.91 years and 62.6% were female. No age differences were observed between genders and randomization groups ( = 0.548,  = 0.791) and groups were homogeneous ( = 0.173,  = 0.443). The intervention group showed a significant increase in vaccination rates after the intervention. For influenza, 79.4-89.7% ( = 0.016); hepatitis B, 29.4-48.5% ( = 0.002); tetanus, 51.5-72.1% ( = 0.007); and pneumonia, 22.1-29.4% ( = 0.049). No significant increase was observed in control group.

CONCLUSION

The orientation to update the vaccination schedule through telephone contact was effective in increasing vaccination rates for influenza, hepatitis B, pneumonia, and tetanus.

TRIAL REGISTRY

RBR-92z99d2 https://ensaiosclinicos.gov.br/rg/RBR-92z99d2.

摘要

目的

评估接受流感、乙肝、肺炎和破伤风疫苗接种计划更新指导的糖尿病患者的疫苗接种率是否有所提高。

方法

于2018年12月至2020年11月进行了一项随机对照试验。样本包括来自圣玛丽亚大学医院内分泌科门诊的139名患者,随机分为干预组(n = 68)和对照组(n = 71)。干预措施包括通过电话更新所评估疾病的疫苗接种计划。

结果

受试者的平均年龄为59.17±12.91岁,62.6%为女性。性别和随机分组之间未观察到年龄差异(p = 0.548,p = 0.791),且各组具有同质性(p = 0.173,p = 0.443)。干预组在干预后疫苗接种率显著提高。流感疫苗接种率从79.4%提高到89.7%(p = 0.016);乙肝疫苗接种率从29.4%提高到48.5%(p = 0.002);破伤风疫苗接种率从51.5%提高到72.1%(p = 0.007);肺炎疫苗接种率从22.1%提高到29.4%(p = 0.049)。对照组未观察到显著提高。

结论

通过电话联系更新疫苗接种计划的指导有效地提高了流感、乙肝、肺炎和破伤风的疫苗接种率。

试验注册

RBR-92z99d2 https://ensaiosclinicos.gov.br/rg/RBR-92z99d2

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ad0/10041585/2d8d676753cd/10.1177_20503121231161193-fig1.jpg

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