Department of Internal Medicine, Hospital Severo Ochoa, Leganés, Spain.
Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/Universidad de Sevilla, Sevilla, Spain.
Epidemiol Health. 2023;45:e2023036. doi: 10.4178/epih.e2023036. Epub 2023 Mar 18.
In Spain, there has been a recent increase in the mortality rate for chronic obstructive pulmonary disease (COPD) in younger women. This study aimed to analyze trends in the COPD mortality rate in Spain from 1980 to 2020, evaluating any differences between genders and age groups.
Death certificates and mid-year population data were obtained from the Spanish National Institute of Statistics. For both genders, age group-specific and standardized (overall and truncated) rates were calculated by the direct method using the world standard population. The data were analyzed using the joinpoint regression method.
In both men and women, the number of COPD deaths increased from 1980 to 1999 (average annual increase of 7% in men and 4% in women), while from 1999 onwards, deaths decreased by -1.0% per year in both genders. In women, there was a significant final period of increase in the 55-59 to 70-74 age groups and a slowing of the decline in the over 75 age group. Additionally, an increase in mortality for the truncated rates was observed for women between 2006 and 2020. In men under 70 years of age, there was an initial period in which death rates remained stable or significantly increased, followed by a period in which they decreased significantly.
Our study shows age and gender differences in COPD mortality trends in Spain. Although the data show a downward trend, we have identified a worrying increase in the truncated rates in women for the last few years.
在西班牙,年轻女性慢性阻塞性肺疾病(COPD)的死亡率近期有所上升。本研究旨在分析 1980 年至 2020 年期间西班牙 COPD 死亡率的趋势,并评估性别和年龄组之间的差异。
从西班牙国家统计局获取死亡证明和年中人口数据。对于男性和女性,使用直接法按年龄组计算特定的和标准化的(总体和截断)死亡率,使用世界标准人口进行标准化。使用连接点回归方法对数据进行分析。
在男性和女性中,COPD 死亡人数从 1980 年至 1999 年增加(男性每年平均增加 7%,女性每年增加 4%),而从 1999 年起,两性的死亡人数每年减少 1.0%。在女性中,55-59 岁至 70-74 岁年龄组的最后一个增长期显著,75 岁以上年龄组的下降速度放缓。此外,在 2006 年至 2020 年期间,女性的截断率死亡率增加。在 70 岁以下的男性中,死亡率最初保持稳定或显著增加,随后显著下降。
本研究表明西班牙 COPD 死亡率趋势存在年龄和性别差异。尽管数据显示呈下降趋势,但我们发现过去几年女性的截断率令人担忧地增加。