Thacker Stephen A
Pediatrics, Medical University of South Carolina, Charleston, USA.
Cureus. 2023 Feb 26;15(2):e35482. doi: 10.7759/cureus.35482. eCollection 2023 Feb.
Invasive disease (IPD) remains a serious cause of morbidity and loss of life in children and adults worldwide. While pneumococcal vaccines have reduced the frequency of invasive pneumococcal disease, the emergence of invasive non-vaccine serotypes has mandated the development of novel pneumococcal vaccines to further protect against these emerging serotypes. We present a case of a non-vaccine serotype invasive pneumococcal disease-causing septic shock, meningitis, and stroke in a previously healthy and appropriately vaccinated 23-month-old male.
侵袭性疾病(IPD)仍然是全球儿童和成人发病和死亡的一个严重原因。虽然肺炎球菌疫苗降低了侵袭性肺炎球菌疾病的发生率,但侵袭性非疫苗血清型的出现促使人们研发新型肺炎球菌疫苗,以进一步预防这些新出现的血清型。我们报告一例由非疫苗血清型引起的侵袭性肺炎球菌疾病,该疾病导致一名23个月大、此前健康且已适当接种疫苗的男性发生感染性休克、脑膜炎和中风。