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复杂性侵袭性肺炎球菌性脑膜炎:凸显新型肺炎球菌疫苗的应用价值

Complicated Invasive Pneumococcal Meningitis: Highlighting the Value of Implementing New Pneumococcal Vaccines.

作者信息

Thacker Stephen A

机构信息

Pediatrics, Medical University of South Carolina, Charleston, USA.

出版信息

Cureus. 2023 Feb 26;15(2):e35482. doi: 10.7759/cureus.35482. eCollection 2023 Feb.

Abstract

Invasive  disease (IPD) remains a serious cause of morbidity and loss of life in children and adults worldwide. While pneumococcal vaccines have reduced the frequency of invasive pneumococcal disease, the emergence of invasive non-vaccine serotypes has mandated the development of novel pneumococcal vaccines to further protect against these emerging serotypes. We present a case of a non-vaccine serotype invasive pneumococcal disease-causing septic shock, meningitis, and stroke in a previously healthy and appropriately vaccinated 23-month-old male.

摘要

侵袭性疾病(IPD)仍然是全球儿童和成人发病和死亡的一个严重原因。虽然肺炎球菌疫苗降低了侵袭性肺炎球菌疾病的发生率,但侵袭性非疫苗血清型的出现促使人们研发新型肺炎球菌疫苗,以进一步预防这些新出现的血清型。我们报告一例由非疫苗血清型引起的侵袭性肺炎球菌疾病,该疾病导致一名23个月大、此前健康且已适当接种疫苗的男性发生感染性休克、脑膜炎和中风。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2f8/10044317/2bed1fabb5ae/cureus-0015-00000035482-i01.jpg

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