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内侧皮质支撑与解剖复位治疗转子间髋部骨折的比较:有限元分析和生物力学测试。

Positive medial cortical support versus anatomical reduction for trochanteric hip fractures: Finite element analysis and biomechanical testing.

机构信息

The Department of Orthopaedic Surgery, Yangpu Hospital, Tongji University School of Medicine, 450 Tengyue Road, Shanghai 200090, China; Department of Orthopedics, Shanghai Fifth People's Hospital, Fudan University, 801 Heqing Road, Shanghai 200240, China.

The Department of Orthopaedic Surgery, Yangpu Hospital, Tongji University School of Medicine, 450 Tengyue Road, Shanghai 200090, China.

出版信息

Comput Methods Programs Biomed. 2023 Jun;234:107502. doi: 10.1016/j.cmpb.2023.107502. Epub 2023 Mar 24.

Abstract

BACKGROUND AND OBJECTIVES

The anatomical reduction (AR) is usually considered the best option for fractures. Nevertheless, in unstable trochanteric hip fractures (UTHF), previous clinical reports found that the positive medial cortical support (PMCS, an over-reduction technique) attained higher mechanical stability, but this challenging clinical finding still needs experimental validation.

METHODS

This study constructed in-silico and biomechanical PMCS and AR models, with the use of the most clinically-representative geometry design of fracture models, the multi-directional design in FE analysis, and the subject-specific (osteoporotic) bone material properties, to make the models better mimic the actual condition in clinical settings. Then multiple performance variables (von-Mises stress, strain, integral axial stiffness, displacement, structural changes, etc.) were assessed to uncover details of integral and regional stability.

RESULTS

Among in-silico comparison, PMCS models showed significantly lower maximum displacement than AR models, and the maximum von Mises stress of implants (MVMS-I) was significantly lower in PMCS models than in AR models (highest MVMS-I in -30°-A3-AR of 1055.80 ± 93.37 MPa). Besides, PMCS models had significantly lower maximum von Mises stress along fracture surfaces (MVMS-F) (highest MVMS-F in 30°-A2-AR of 416.40 ± 38.01 MPa). Among biomechanical testing comparison, PMCS models showed significantly lower axial displacement. Significantly lower change of neck-shaft angle (CNSA) was observed in A2-PMCS models. A fair amount of AR models converted into the obvious negative medial cortical support (NMCS) condition, whereas all PMCS models kept the PMCS condition. The results were also validated through comparison to previous clinical data.

CONCLUSIONS

The PMCS is superior to the AR in the UTHF surgery. The current study opens up the second thought of the role of over-reduction technique in bone surgery.

摘要

背景与目的

解剖复位(AR)通常被认为是骨折的最佳选择。然而,在不稳定型转子间髋部骨折(UTHF)中,之前的临床报告发现,内侧皮质支持的过度复位(PMCS,一种过复位技术)可获得更高的机械稳定性,但这一具有挑战性的临床发现仍需要实验验证。

方法

本研究构建了基于计算机的 PMCS 和 AR 模型,使用最具临床代表性的骨折模型几何设计、FE 分析中的多方向设计以及特定于个体(骨质疏松)的骨材料特性,使模型更好地模拟临床环境中的实际情况。然后评估了多个性能变量(von-Mises 应力、应变、整体轴向刚度、位移、结构变化等),以揭示整体和局部稳定性的细节。

结果

在计算机模拟比较中,PMCS 模型的最大位移明显低于 AR 模型,PMCS 模型中植入物的最大 von Mises 应力(MVMS-I)明显低于 AR 模型(最高 MVMS-I 在-30°-A3-AR 为 1055.80 ± 93.37 MPa)。此外,PMCS 模型中骨折表面的最大 von Mises 应力(MVMS-F)明显较低(在 30°-A2-AR 中最高,为 416.40 ± 38.01 MPa)。在生物力学测试比较中,PMCS 模型的轴向位移明显较低。A2-PMCS 模型的颈干角变化(CNSA)明显较低。大量 AR 模型转变为明显的负内侧皮质支持(NMCS)状态,而所有 PMCS 模型均保持 PMCS 状态。研究结果还通过与之前的临床数据进行比较得到了验证。

结论

PMCS 在 UTHF 手术中优于 AR。本研究开启了对骨外科中过度复位技术作用的第二种思考。

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