玻璃体视网膜淋巴瘤中显著视网膜下浸润的快速自发消退
Rapid, Spontaneous Resolution of Prominent Subretinal Infiltrate in Vitreoretinal Lymphoma.
作者信息
Gong Dan, Aronow Mary E, Eliott Dean
机构信息
Retina Service, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
出版信息
J Vitreoretin Dis. 2021 May 5;6(1):80-85. doi: 10.1177/24741264211009804. eCollection 2022 Jan-Feb.
PURPOSE
This case report describes a patient with vitreoretinal lymphoma who subacutely developed a large, peripapillary subretinal infiltrate that rapidly and spontaneously resolved.
METHODS
A case report is presented.
RESULTS
A 65-year-old Asian-American woman was referred for evaluation of a dense, peripapillary subretinal infiltrate in the left eye. A diagnostic vitrectomy revealed large, atypical lymphocytes with irregularly shaped nuclei, and mutational testing was positive for myeloid differentiation primary response 88 (). Prior to surgery, the patient's subretinal infiltrate had begun to resolve spontaneously, a process that continued after surgery without initiation of systemic or local ocular therapy.
CONCLUSIONS
Patients with vitreoretinal lymphoma may present with transient, subretinal infiltrates that can resolve without treatment.
目的
本病例报告描述了一名玻璃体视网膜淋巴瘤患者，其亚急性出现了一个大的视乳头周围视网膜下浸润灶，该浸润灶迅速且自发消退。
方法
呈现一例病例报告。
结果
一名65岁的亚裔美国女性因左眼视乳头周围致密的视网膜下浸润灶而接受评估。诊断性玻璃体切除术显示有大的、具有不规则形核的非典型淋巴细胞，髓样分化主要反应88（）的突变检测呈阳性。在手术前，患者的视网膜下浸润灶已开始自发消退，在手术后该过程仍在继续，未开始全身或局部眼部治疗。
结论
玻璃体视网膜淋巴瘤患者可能出现短暂的视网膜下浸润灶，可不经治疗而消退。
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