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利用连续血糖监测设备成功停用皮下胰岛素治疗的2型失代偿性糖尿病

Type 2 Decompensated Diabetes Mellitus Weaned off Subcutaneous Insulin Therapy by Utilizing a Continuous Glucose Monitoring Device.

作者信息

Manov AndreyI, Dhillon Gundip S, Chauhan Sukhjinder, Asllanaj Blerina, Uy Erie S

机构信息

Internal Medicine, MountainView Hospital, Las Vegas, USA.

出版信息

Cureus. 2023 Mar 31;15(3):e36970. doi: 10.7759/cureus.36970. eCollection 2023 Mar.

DOI:10.7759/cureus.36970
PMID:37012944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10065865/
Abstract

A case series was conducted on three patients diagnosed with decompensated type 2 diabetes mellitus (T2DM) who had hemoglobin A1c (HbA1c) levels ranging from 9.5% to above 14%. Patients were self-monitoring blood glucose (SMBG) levels four times a day. These patients were seen at the resident continuity clinic and were placed on continuous glucose monitor (CGM) devices to monitor their blood glucose levels. To improve the effectiveness of the treatment closely, a CGM team consisting of transitional year and internal medicine residents was arranged. The CGM team provided comprehensive education and written instructions on dietary changes, insulin administration, and physical activity at monthly follow-up appointments. Before the instructions were given to the patients, they were reviewed and approved by the supervising attending physician who was a board-certified endocrinologist. Our CGM team successfully managed these three patients with T2DM by tailoring their insulin regimens by using real-time CGM data. With the help of close CGM monitoring, patients were successfully transitioned from requiring multiple subcutaneous insulin injections to oral anti-diabetics. After the transition, patients' T2DM remained well-controlled with an HbA1c level of less than 7% at their follow-up appointments. This case series demonstrated the successful implementation of CGM-guided T2DM treatment in a continuity clinic managed by residents. To our knowledge, the use of CGM-guided T2DM treatment in the setting of resident care has never been reported in the United States before. This may serve as a benchmark for other continuity clinics which residents run across the country.

摘要

对三名被诊断为失代偿性2型糖尿病(T2DM)且糖化血红蛋白(HbA1c)水平在9.5%至14%以上的患者进行了一项病例系列研究。患者每天自我监测四次血糖(SMBG)水平。这些患者在住院医师连续性诊所就诊,并佩戴连续血糖监测(CGM)设备以监测其血糖水平。为密切提高治疗效果,安排了一个由过渡年和内科住院医师组成的CGM团队。CGM团队在每月的随访预约中提供关于饮食变化、胰岛素给药和体育活动的全面教育及书面指导。在向患者提供指导之前,由一名获得董事会认证的内分泌科主治医师对指导内容进行审核和批准。我们的CGM团队通过利用实时CGM数据调整胰岛素治疗方案,成功管理了这三名T2DM患者。在密切的CGM监测帮助下,患者成功地从需要多次皮下注射胰岛素转变为口服抗糖尿病药物。转变后,患者的T2DM在随访预约时仍得到良好控制,HbA1c水平低于7%。该病例系列证明了在住院医师管理的连续性诊所中成功实施CGM指导的T2DM治疗。据我们所知,在美国以前从未有过在住院医师护理环境中使用CGM指导T2DM治疗的报道。这可能为全国其他由住院医师管理的连续性诊所提供一个基准。

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