Health Economics and Market Access, DePuy Synthes, Leeds, UK.
Epidemiology and Real-World Data Sciences, Johnson and Johnson MedTech, 410 George Street, New Brunswick, NJ, 08933, USA.
J Orthop Surg Res. 2023 Apr 4;18(1):273. doi: 10.1186/s13018-023-03750-4.
The incidence of total knee arthroplasty (TKA) surgery performed in the outpatient setting has increased as a result of improved perioperative recovery protocols, bundled payments, and challenges brought by the coronavirus disease of 2019 (COVID-19) pandemic on health systems. This study evaluates early postoperative clinical and economic outcomes of patients treated in the inpatient vs outpatient setting using the Attune Knee System (AKS).
Patients with an elective, primary TKA implanted with the AKS, from Q4 2015 to Q1 2021, were identified within the Premier Healthcare Database. The index was defined as the admission date for inpatient cases and the service day for outpatient procedures. Inpatient and outpatient cases were matched on patient characteristics. Outcomes included 90-day all-cause readmissions, 90-day knee reoperations, and index- and 90-day costs of care. Generalized linear models were used to evaluate outcomes (Reoperation: binomial distribution; costs: Gamma distribution with log link).
Before matching, 39,337 inpatient and 9,365 outpatient cases were identified, with greater comorbidities in the inpatient cohort. The outpatient cohort had a lower average Elixhauser Index (EI) compared to the inpatient cohort (1.94 (standard deviation (SD): 1.46) vs 2.17 (SD: 1.53), p < 0.001), and the rates for each individual comorbidities were also slightly lower in the outpatient compared to the inpatient cohorts. Post-match, 9,060 patients were retained in each cohort [mean age: ~ 67, EI = 1.9 (SD: 1.5), 40% male]. Post-match comorbidity rates were similar between inpatient and outpatient cohorts (outpatient EI: 1.94 (SD: 1.44)-inpatient EI: 1.96 (SD: 1.45), p = 0.3516): in both, 54.1% of patients had an EI between 1 and 2, and 5.1% had an EI ≥ 5. No differences were observed in 3-month reoperation rates (0.6% in outpatient, 0.7% in inpatient cohort). Index and post-index 90-day costs were lower in the outpatient vs inpatient cases [(savings for index-only costs: $2,295 (95% CI: $1,977-$2,614); 90 days post-index knee-related care only: $2,540 (95% CI: $2,205-$2,876); 90 days post-index all-cause care: $2,679 (95% CI: $2,322-$3,036)].
Compared to matched inpatient cases, outpatient TKA cases treated with AKS showed similar 90-day outcomes, at lower cost.
随着围手术期恢复方案的改进、捆绑支付以及 2019 年冠状病毒病(COVID-19)大流行对卫生系统带来的挑战,门诊全膝关节置换术(TKA)的发病率有所增加。本研究使用 Attune 膝关节系统(AKS)评估了在住院和门诊环境中治疗的患者的早期术后临床和经济结局。
从 2015 年第四季度到 2021 年第一季度,在 Premier Healthcare Database 中确定了接受择期、初次 TKA 植入 AKS 的患者。指数定义为住院病例的入院日期和门诊手术的服务日。对住院和门诊病例按患者特征进行匹配。结果包括 90 天内全因再入院、90 天内膝关节再次手术以及指数日和 90 天内的护理费用。使用广义线性模型评估结果(再次手术:二项分布;成本:对数链接的伽马分布)。
在匹配之前,确定了 39337 例住院和 9365 例门诊病例,住院组合并症更多。与住院组相比,门诊组的平均 Elixhauser 指数(EI)较低(1.94(标准差(SD):1.46)比 2.17(SD:1.53),p<0.001),门诊组每个合并症的发生率也略低于住院组。匹配后,每组保留 9060 例患者[平均年龄:~67 岁,EI=1.9(SD:1.5),40%为男性]。住院和门诊组的合并症发生率相似(门诊 EI:1.94(SD:1.44)-住院 EI:1.96(SD:1.45),p=0.3516):两者均有 54.1%的患者 EI 在 1 到 2 之间,5.1%的患者 EI≥5。门诊和住院组的 3 个月再手术率无差异(门诊 0.6%,住院组 0.7%)。与住院病例相比,门诊病例的指数日和指数后 90 天的成本较低[仅指数成本的节省:$2295(95%CI:$1977-$2614);指数后 90 天仅膝关节相关护理费用:$2540(95%CI:$2205-$2876);指数后 90 天所有原因护理费用:$2679(95%CI:$2322-$3036)]。
与匹配的住院病例相比,使用 AKS 治疗的门诊 TKA 病例的 90 天结局相似,但成本更低。