College of Nursing and Health Sciences, Flinders University, GPO Box 2100, Adelaide, South Australia, 5001, Australia.
Int J Ment Health Nurs. 2023 Oct;32(5):1243-1258. doi: 10.1111/inm.13148. Epub 2023 Apr 6.
This integrative review explores the current pro re nata (PRN) medication practice in acute adult mental health settings. PRN medication is commonly used in acute mental health settings but there is lack of evidence of effectiveness of this practice. PRN medications have a number of adverse effects and increase the risk of morbidity in patients with a mental illness. Articles were identified from MEDLINE, CINAHL, Scopus, PubMed, PsycINFO, and Web of Science database. The STROBE critical appraisal tool was used to evaluate the quality of evidence, and inductive thematic analysis was used to extract main themes. Five themes regarding prescription practices, poor documentation, reasons to administer, medication misuse, and insufficient use of non-pharmacological interventions emerged among the 12 eligible articles. The study identified PRN medication practice gaps in adult mental health settings included insufficient documentation practice, underuse of therapeutic non-pharmacological interventions, and significant variability in PRN medication practice across the mental health professionals due to different levels of knowledge and experience.
这篇综合评论探讨了目前急性成人精神卫生环境中按需(PRN)用药的实践情况。PRN 药物在急性精神卫生环境中经常使用,但这种做法的有效性缺乏证据。PRN 药物有许多不良反应,并增加了精神疾病患者发病的风险。文章从 MEDLINE、CINAHL、Scopus、PubMed、PsycINFO 和 Web of Science 数据库中确定。使用 STROBE 关键评估工具来评估证据的质量,并使用归纳主题分析来提取主要主题。在 12 篇合格文章中出现了关于处方实践、记录不良、给药原因、药物滥用和非药物干预措施使用不足的五个主题。该研究确定了成人精神卫生环境中 PRN 药物实践中的差距,包括记录实践不足、治疗性非药物干预措施使用不足以及由于知识和经验水平不同,精神卫生专业人员之间的 PRN 药物实践存在显著差异。