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尼泊尔盲人综合学校及前往三级眼科医院就诊儿童中重度视力损害和失明的原因:尼泊尔儿童视力损害(NPVI)研究

Causes of Moderate to Severe Visual Impairment and Blindness Among Children in Integrated Schools for the Blind and Visiting a Tertiary Eye Hospital in Nepal: The Nepal Pediatric Visual Impairment (NPVI) Study.

作者信息

Adhikari Srijana, van Nispen Ruth Marie Antoinette, Elsman Ellen Bernadette Maria, van Rens Fleur, van Rens Ger

机构信息

Department of Pediatric Ophthalmology and Strabismus, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.

Department of Ophthalmology, VU University Medical Centre and the Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.

出版信息

Clin Ophthalmol. 2023 Apr 3;17:1025-1034. doi: 10.2147/OPTH.S394890. eCollection 2023.

Abstract

PURPOSE

To study the causes of moderate and severe visual impairment (VI) and blindness and its changing trends in Nepalese children.

PATIENTS AND METHODS

A cross-sectional descriptive study was conducted. Participants, aged 7 to 17 years were recruited from integrated schools for the blind and the outpatient department of a tertiary eye hospital in Kathmandu. VI and blindness were categorized according to World Health Organization (WHO) categories and its protocol for eye examination of children with blindness and VI was followed. Findings were compared to former studies from Nepal.

RESULTS

A total of 200 children were included, of whom 45% had moderate VI, 5% had severe VI, and 50% were blind. Mean age of children with VI and blindness was 11.1 (SD = 3.3) and 12.9 (SD = 3) years, respectively. Forty percent of children with VI and 38% of blind children were female. In our study, retina (39%) and whole globe (32%) were the most common anatomical site of involvement in children with VI and blindness, respectively, while cornea was the most common anatomical site of involvement in former studies. Heredity (43%) was the most common etiological factor although in 24.5% of all children, etiology was unknown. In 43.5% of children, blindness and VI was due to avoidable causes.

CONCLUSION

In relatively many children, the etiology of VI and blindness could be either prevented or treated. Compared to former studies from Nepal, there is a changing trend in the etiology of severe VI and blindness.

摘要

目的

研究尼泊尔儿童中重度视力损害(VI)和失明的原因及其变化趋势。

患者与方法

开展了一项横断面描述性研究。从加德满都一所综合性盲人学校和一家三级眼科医院的门诊部招募了7至17岁的参与者。根据世界卫生组织(WHO)的分类对视力损害和失明进行分类,并遵循其针对失明和视力损害儿童的眼科检查方案。将研究结果与尼泊尔以前的研究进行比较。

结果

共纳入200名儿童,其中45%为中度视力损害,5%为重度视力损害,50%为失明。视力损害和失明儿童的平均年龄分别为11.1岁(标准差=3.3)和12.9岁(标准差=3)。40%的视力损害儿童和38%的失明儿童为女性。在我们的研究中,视网膜(39%)和整个眼球(32%)分别是视力损害和失明儿童最常见的受累解剖部位,而在以前的研究中,角膜是最常见的受累解剖部位。遗传(43%)是最常见的病因,尽管在所有儿童中有24.5%的病因不明。在43.5%的儿童中,失明和视力损害是由可避免的原因导致的。

结论

在相当多的儿童中,视力损害和失明的病因是可以预防或治疗的。与尼泊尔以前的研究相比,重度视力损害和失明的病因有变化趋势。

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