乳腺癌幸存者中多种合并症的存在情况及结直肠癌筛查利用情况

Presence of Multi-Morbidities and Colorectal Cancer Screening Utilization among Breast Cancer Survivors.

作者信息

Tsai Meng-Han, Grunert Caitlyn, Vo Jacqueline B, Moore Justin X, Guha Avirup

机构信息

Cancer Prevention, Control & Population Health Program, Georgia Cancer Center, Department of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Georgia Prevention Institute, Augusta University, Augusta, GA 30912, USA.

出版信息

Cancers (Basel). 2023 Mar 30;15(7):2077. doi: 10.3390/cancers15072077.

DOI:10.3390/cancers15072077

PMID:37046737

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10093549/

Abstract

PURPOSE

Our study aimed to examine the association between the presence of chronic diseases with guideline-concordant colorectal cancer (CRC) screening utilization among breast cancer survivors.

METHODS

We analyzed data among women with a history of breast cancer from the 2016, 2018, and 2020 Behavioral Risk Factor Surveillance System. Receipt of guideline-concordant CRC screening was the outcome of interest. Diabetes, coronary heart disease/myocardial infarction, stroke, chronic obstructive pulmonary disease, emphysema/chronic bronchitis, arthritis, depressive disorder, or kidney diseases were included in chronic disease conditions.

RESULTS

Among 1324 survivors, those with multi-morbidities (3+ chronic diseases; 88.3%) had higher CRC screening use compared to those with one (84.4%) or two (85.4%) diseases (-value < 0.05). In multivariable analysis, survivors with multi-morbidities were two times more likely to have CRC screening compared to those with only one disease (OR, 2.10; 95% CI, 1.11-3.98). Among survivors with multi-morbidities, Black women (OR, 14.07; 95% CI, 5.61-35.27), and those with frequent poor physical health (OR, 3.32; 95% CI, 1.57-7.00) were positively associated with CRC screening use. Conversely, survivors with frequent poor mental health were 67% less likely to receive CRC screening (OR, 0.33; 95% CI, 0.14-0.74).

CONCLUSION

Among breast cancer survivors, multi-morbidities were positively associated with CRC screening.

摘要

目的

我们的研究旨在探讨乳腺癌幸存者中慢性病的存在与符合指南的结直肠癌（CRC）筛查利用率之间的关联。

方法

我们分析了2016年、2018年和2020年行为危险因素监测系统中乳腺癌病史女性的数据。接受符合指南的CRC筛查是感兴趣的结果。慢性病状况包括糖尿病、冠心病/心肌梗死、中风、慢性阻塞性肺疾病、肺气肿/慢性支气管炎、关节炎、抑郁症或肾脏疾病。

结果

在1324名幸存者中，患有多种疾病（3种及以上慢性病；88.3%）的人CRC筛查使用率高于患有1种（84.4%）或2种（85.4%）疾病的人（P值<0.05）。在多变量分析中，患有多种疾病的幸存者进行CRC筛查的可能性是仅患一种疾病的幸存者的两倍（比值比，2.10；95%置信区间，1.11-3.98）。在患有多种疾病的幸存者中，黑人女性（比值比，14.07；95%置信区间，5.61-35.27）和身体健康状况经常较差的人（比值比，3.32；95%置信区间，1.57-7.00）与CRC筛查使用率呈正相关。相反，心理健康状况经常较差的幸存者接受CRC筛查的可能性降低67%（比值比，0.33；95%置信区间，0.14-0.74）。