Carrascosa J M, Vilarrasa E, Belinchón I, Herranz P, Crespo J, Guimerá F, Olveira A
Departamento de Dermatología, Hospital Universitario Germans Trias i Pujol, Universitat Autònoma de Barcelona, IGTP Badalona, Barcelona, Spain.
Departamento de Dermatología, Hospital Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Actas Dermosifiliogr. 2023 May;114(5):T392-T401. doi: 10.1016/j.ad.2023.04.013. Epub 2023 Apr 15.
Recent years have seen concerted efforts to understand the relation between psoriasis and metabolic-associated fatty liver disease (MAFLD). Not only is MALFD diagnosed more often in patients with psoriasis, but its clinical course is also more aggressive. A common approach is therefore needed to enable early detection of liver disease coincident with psoriasis. Especially important is an analysis of risks and benefits of potentially hepatotoxic treatments. This consensus paper presents the recommendations of a group of experts in dermatology and hepatology regarding screening for MALFD as well as criteria for monitoring patients and referring them to hepatologists when liver disease is suspected.
近年来,人们为了解银屑病与代谢相关脂肪性肝病(MAFLD)之间的关系付出了共同努力。不仅MAFLD在银屑病患者中诊断更为频繁,而且其临床病程也更具侵袭性。因此,需要一种通用方法来实现与银屑病同时发生的肝病的早期检测。特别重要的是分析潜在肝毒性治疗的风险和益处。本共识文件提出了一组皮肤科和肝病学专家关于MAFLD筛查的建议,以及监测患者和在怀疑有肝病时将患者转诊给肝病专家的标准。