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2016 年至 2019 年日本肠胃病学委员会认证医师收到的药品付款的横断面分析。

Cross-sectional analysis of pharmaceutical payments to Japanese board-certified gastroenterologists between 2016 and 2019.

机构信息

School of Medicine, Tohoku University, Sendai, Miyagi, Japan

School of Medicine, Hamamatsu University, Hamamatsu, Japan.

出版信息

BMJ Open. 2023 Apr 18;13(4):e068237. doi: 10.1136/bmjopen-2022-068237.

Abstract

OBJECTIVES

Limited evidence is available regarding the financial relationships between gastroenterologists and pharmaceutical companies in Japan. This study analysed the magnitude, prevalence and trends of personal payments made by major pharmaceutical companies to board-certified gastroenterologists in Japan in recent years.

DESIGN

Cross-sectional analysis SETTING AND PARTICIPANTS: Using payment data publicly disclosed by 92 major pharmaceutical companies, this study examined the non-research payments made to all board-certified gastroenterologists by the Japanese Society of Gastroenterology.

PRIMARY AND SECONDARY OUTCOME MEASURES

The primary outcomes were payment amounts, the prevalence of gastroenterologists receiving payments, yearly trends in per-gastroenterologist payment values and the number of gastroenterologists with payments. Additionally, we evaluated the differences in payments among influential gastroenterologists, including clinical practice guideline authors, society board member gastroenterologists and other general gastroenterologists.

RESULTS

Approximately 52.8% of all board-certified gastroenterologists received a total of US$89 151 253, entailing 134 249 payment contracts as the reimbursement for lecturing, consulting and writing, from 84 pharmaceutical companies between 2016 and 2019. The average and median payments per gastroenterologist were US$7670 (SD: US$26 842) and US$1533 (IQR: US$582-US$4781), respectively. The payment value per gastroenterologist did not significantly change during the study period, while the number of gastroenterologists with payments decreased by -1.01% (95% CI: -1.61% to -0.40%, p<0.001) annually. Board member gastroenterologists (median: US$132 777) and the guideline authoring gastroenterologists (median: US$106 069) received 29.9 times and 17.3 times higher payments, respectively, than general gastroenterologists (median: US$284).

CONCLUSION

Most gastroenterologists received personal payments from pharmaceutical companies, but only very few influential gastroenterologists with authority accepted substantial amounts in Japan. There should be transparent and rigorous management strategies for financial conflicts of interest among gastroenterologists working in influential positions.

摘要

目的

日本胃肠病学家与制药公司之间的财务关系相关证据有限。本研究分析了近年来日本主要制药公司向经董事会认证的胃肠病学家支付的个人款项的规模、流行率和趋势。

设计

横断面分析

背景和参与者

本研究使用 92 家主要制药公司公开披露的支付数据,检查了日本胃肠病学会向所有经董事会认证的胃肠病学家支付的非研究性款项。

主要和次要结果

主要结果是支付金额、接受支付的胃肠病学家的流行率、每位胃肠病学家支付金额的年度趋势以及有支付记录的胃肠病学家人数。此外,我们还评估了有影响力的胃肠病学家(包括临床实践指南作者、学会理事会成员胃肠病学家和其他普通胃肠病学家)之间的支付差异。

结果

在 2016 年至 2019 年期间,约有 52.8%的所有经董事会认证的胃肠病学家从 84 家制药公司收到了总计 8915.13 万美元的款项,其中包括演讲、咨询和写作的报销,共涉及 134249 笔支付合同。每位胃肠病学家的平均和中位数支付金额分别为 7670 美元(SD:26842 美元)和 1533 美元(IQR:582-4781 美元)。研究期间每位胃肠病学家的支付金额没有显著变化,而有支付记录的胃肠病学家数量每年减少 1.01%(95%CI:-1.61%至-0.40%,p<0.001)。理事会成员胃肠病学家(中位数:132777 美元)和指南制定胃肠病学家(中位数:106069 美元)的支付金额分别是普通胃肠病学家(中位数:284 美元)的 29.9 倍和 17.3 倍。

结论

大多数胃肠病学家从制药公司获得个人报酬,但在日本,只有极少数有影响力的权威胃肠病学家接受了大量报酬。在有影响力的职位上工作的胃肠病学家应制定透明和严格的财务利益冲突管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b0c/10124293/c94735d7b0e4/bmjopen-2022-068237f01.jpg

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