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两阶段翻修策略中的序贯重复胫骨结节截骨术:治疗慢性感染性膝关节置换的更佳方法?

Sequential repeated tibial tubercle osteotomy in a two-stage exchange strategy: a superior approach to treating a chronically infected knee arthroplasty?

机构信息

Universitat Autònoma de Barcelona (UAB), Orthopaedic Surgery Department, Vall d'Hebron University Hospital, Barcelona, Spain.

Septic and Reconstructive Surgery Unit (UCSO), Orthopaedic Surgery Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), Barcelona, Spain.

出版信息

Eur J Orthop Surg Traumatol. 2023 Dec;33(8):3347-3355. doi: 10.1007/s00590-023-03548-4. Epub 2023 Apr 20.

DOI:10.1007/s00590-023-03548-4
PMID:37079110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10651709/
Abstract

PURPOSE

Surgical approach can impact the reliability of the debridement after a chronic total knee periprosthetic joint infection (PJI), a factor of utmost importance to eradicate the infection. The most adequate knee surgical approach in cases of PJI is a matter of debate. The purpose of this study was to determine the influence of performing a tibial tubercle osteotomy (TTO) in a two-stage exchange protocol for knee PJI treatment.

METHODS

Retrospective cohort study examining patients managed with two-stage arthroplasty due to chronic knee PJI (2010-2019). Performance and timing of the TTO were collected. Primary end-point was infection control with a minimum FU of 12 months and according to internationally accepted criteria. Correlation between TTO timing and reinfection rate was reviewed.

RESULTS

Fifty-two cases were finally included. Overall success (average follow-up: 46.2 months) was 90.4%. Treatment success was significantly higher among cases addressed using TTO during the second stage (97.1% vs. 76.5%, p value 0.03). Only 4.8% of the patients relapsed after performing a sequential repeated TTO, that is, during both first and second stages, compared to 23.1% cases in which TTO was not done (p value 0.28). No complications were observed among patients in the TTO group with a significant decrease in soft tissue necrosis (p: 0.052).

CONCLUSION

Sequential repeated tibial tubercle osteotomy during a two-stage strategy is a reasonable option and offers high rates of infection control in complex cases of knee PJI with a low rate of complications.

摘要

目的

手术入路可能会影响慢性全膝关节假体周围关节感染(PJI)清创的可靠性,这是消除感染的最重要因素。在 PJI 病例中,最合适的膝关节手术入路仍存在争议。本研究旨在确定在膝关节 PJI 两阶段置换方案中进行胫骨结节截骨术(TTO)的影响。

方法

回顾性队列研究,研究对象为 2010 年至 2019 年因慢性膝关节 PJI 接受两阶段关节置换的患者。收集 TTO 的执行情况和时间。主要终点是根据国际公认的标准,在 12 个月的最低随访时间内控制感染。回顾 TTO 时间与再感染率之间的相关性。

结果

最终纳入 52 例病例。总体成功率(平均随访 46.2 个月)为 90.4%。在第二期手术中进行 TTO 的病例治疗成功率明显更高(97.1% vs. 76.5%,p 值 0.03)。仅 4.8%的患者在进行顺序重复 TTO 后复发,即在第一和第二期均进行 TTO,而未进行 TTO 的患者中复发率为 23.1%(p 值 0.28)。TTO 组患者无并发症,软组织坏死发生率显著降低(p:0.052)。

结论

在两阶段策略中,顺序重复胫骨结节截骨术是一种合理的选择,可为膝关节 PJI 复杂病例提供高感染控制率,且并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/90804170e21b/590_2023_3548_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/218a3ee9d066/590_2023_3548_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/45923a777f8e/590_2023_3548_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/c247339c5bff/590_2023_3548_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/246326732a0c/590_2023_3548_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/90804170e21b/590_2023_3548_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/218a3ee9d066/590_2023_3548_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/45923a777f8e/590_2023_3548_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/c247339c5bff/590_2023_3548_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/246326732a0c/590_2023_3548_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f10e/10651709/90804170e21b/590_2023_3548_Fig5_HTML.jpg

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