Int J Oral Maxillofac Implants. 2023 Mar-Apr;38(2):259-267. doi: 10.11607/jomi.10042.
To evaluate the diagnostic accuracy of bone loss/bone levels, as detected after 5 years of implant function, in identifying patients who suffered implant failures in the following 5 years. Data on radiographic measurements of marginal bone levels at prosthesis placement and after 5 years of function were retrospectively retrieved from 11 previous publications. Included patients were allocated into different subgroups with regard to bone loss/bone level during/after 5 years in function, respectively. A diagnostic test was used to estimate the accuracy of finding patients/jaws/implants at risk for a future implant failure by calculating sensitivity, specificity, positive predictive values (PPVs), and negative predictive values (NPVs) in different subgroups, respectively. Altogether, 749 treated jaws (723 patients/3,363 implants) were included in the study group. Treated jaws in the high-level subgroups presented an overall higher risk of implant failures from 5 to 10 years in function ( < .05). Many treated jaws/implants were allocated into the high-level groups, but the proportions of implant failures were low in these groups. The diagnostic test comparing high- and low-level groups with and without implant failures showed low accuracy to predict implant failures; the PPV ranged from 4% to 33%. Lower PPVs were observed for diagnostic tests for individual implants (range: 4% to 6%). More severe bone loss was associated with higher risk of future implant failure. However, many patients/ implants with obvious bone loss in the study group and low prevalence of implant failures at the 10-year examination resulted in poor accuracy in identifying individual patients or implants at risk for failure. This suggests that it is difficult to predict future implant failures based only on radiographic measurements.
评估植入物功能 5 年后骨量/骨水平的诊断准确性,以识别随后 5 年内发生植入物失败的患者。从之前的 11 项研究中回顾性地检索了假体放置和功能 5 年后边缘骨水平的放射学测量数据。根据功能期间/之后 5 年内的骨量/骨水平,将纳入的患者分别分配到不同的亚组中。使用诊断测试分别计算不同亚组中发现未来发生植入物失败风险的患者/颌骨/植入物的准确性,以计算灵敏度、特异性、阳性预测值(PPV)和阴性预测值(NPV)。共有 749 个治疗颌骨(723 名患者/3363 个植入物)被纳入研究组。高水平亚组的治疗颌骨在功能 5 至 10 年内发生植入物失败的总体风险更高(<0.05)。许多治疗颌骨/植入物被分配到高水平组,但这些组中的植入物失败比例较低。比较高、低水平组和有、无植入物失败的诊断测试显示,预测植入物失败的准确性较低;PPV 范围为 4%至 33%。对于个别植入物的诊断测试,观察到的 PPV 较低(范围:4%至 6%)。更严重的骨量丢失与未来植入物失败的风险增加相关。然而,研究组中许多患者/植入物的骨量明显丢失,而在 10 年检查中植入物失败的发生率较低,导致难以准确识别有失败风险的个别患者或植入物。这表明仅基于放射学测量很难预测未来的植入物失败。