Department of Nephrology, Shanghai Fifth People's Hospital, Fudan University, 801 Heqing Rd, Shanghai, 200240, China.
BMC Nephrol. 2023 Apr 21;24(1):104. doi: 10.1186/s12882-023-03166-6.
The aim of this study was to identify the prevalence of the depressive symptoms and the factors associated with the depressive symptoms in peritoneal dialysis patients.
A cross-sectional study was carried out to evaluate the prevalence and associated factors of depression in 132 continuous ambulatory peritoneal dialysis patients. Depression was evaluated using Zung Self-Rating Depression Scale. Sociodemographic and clinical characteristic were also investigated. Univariate analysis and multivariate logistic regression analysis were performed to select factors associated with depressive symptoms.
Their median age was 57.5 years, and 58.3% were male. The rate of depressive symptoms in peritoneal dialysis patients was 78.0%. The rate of moderate/severe depressive symptoms was 64.4%. Multivariable logistic regression analysis showed that lower serum hemoglobin was significantly associated with increased risks of depression (OR = 0.989, 95CI%=0.979-0.998, p = 0.023).
Depression was highly prevalent in the peritoneal dialysis patients. Serum hemoglobin was independent risk factor for depressive symptoms in peritoneal dialysis patients.
本研究旨在确定腹膜透析患者抑郁症状的患病率及其相关因素。
采用横断面研究评估了 132 例持续非卧床腹膜透析患者的抑郁发生率及相关因素。采用zung 自评抑郁量表评估抑郁。同时调查社会人口学和临床特征。采用单因素分析和多因素 logistic 回归分析筛选与抑郁症状相关的因素。
患者中位年龄为 57.5 岁,58.3%为男性。腹膜透析患者抑郁症状发生率为 78.0%。中重度抑郁症状发生率为 64.4%。多因素 logistic 回归分析显示,血清血红蛋白较低与抑郁风险增加显著相关(OR=0.989,95%CI=0.979-0.998,p=0.023)。
腹膜透析患者中抑郁症状发生率较高。血清血红蛋白是腹膜透析患者抑郁症状的独立危险因素。