National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Appl Clin Med Phys. 2023 Aug;24(8):e13984. doi: 10.1002/acm2.13984. Epub 2023 Apr 24.
Quality control (QC) is performed routinely through professional guidelines. However, the recommended QC frequency may not be optimal among different institutional settings. Here we propose a novel method for determining the optimal QC frequency using risk matrix (RM) analysis.
A newly installed Magnetic Resonance linac (MR-linac) was chosen as the testing platform and six routine QC items were investigated. Failures of these QC items can adversely affect treatment outcome for the patient. Accordingly, each QC item with its assigned frequency forms a unique failure mode (FM). Using FM-effect analysis (FMEA), the severity (S), occurrence (O), and detection (D) of each FM was obtained. Next, S and D based on RM was used to determine the appropriate QC frequency. Finally, the performance of new frequency for each QC item was evaluated using the metric E = O/D.
One new QC frequency was the same as the old frequency, two new QC frequencies were less than the old ones, and three new QC frequencies were higher than the old ones. For six QC items, E values at the new frequencies were not less than their values at the old frequencies. This indicates that the risk of machine failure is reduced at the new QC frequencies.
The application of RM analysis provides a useful tool for determining the optimal frequencies for routine linac QC. This study demonstrated that linac QC can be performed in a way that maintains high performance of the treatment machine in a radiotherapy clinic.
质量控制(QC)是通过专业指南进行常规操作的。然而,在不同的机构环境中,推荐的 QC 频率可能不是最佳的。在这里,我们提出了一种使用风险矩阵(RM)分析来确定最佳 QC 频率的新方法。
选择新安装的磁共振直线加速器(MR-linac)作为测试平台,研究了六个常规 QC 项目。这些 QC 项目的失败会对患者的治疗效果产生不利影响。因此,每个 QC 项目及其指定的频率形成一个独特的故障模式(FM)。通过故障模式影响分析(FMEA),获得了每个 FM 的严重度(S)、发生度(O)和检测度(D)。接下来,基于 RM 的 S 和 D 用于确定适当的 QC 频率。最后,使用度量 E=O/D 评估每个 QC 项目的新频率性能。
一种新的 QC 频率与旧频率相同,两种新的 QC 频率低于旧频率,三种新的 QC 频率高于旧频率。对于六个 QC 项目,新频率下的 E 值不低于旧频率下的 E 值。这表明在新的 QC 频率下,机器故障的风险降低了。
RM 分析的应用为确定常规直线加速器 QC 的最佳频率提供了有用的工具。本研究表明,直线加速器 QC 可以在保持放射治疗临床中治疗机器高性能的方式下进行。