Patel Raj H, Fagan Kiley, Chitnavis Padma V, Grider Douglas
Dermatology, Edward Via College of Osteopathic Medicine, Monroe, USA.
Dermatology and Mohs Surgery, Virginia Tech Carilion School of Medicine, Roanoke, USA.
Cureus. 2023 Mar 23;15(3):e36598. doi: 10.7759/cureus.36598. eCollection 2023 Mar.
Papuloerythroderma of Ofuji (PEO) is a rare skin disorder characterized by a distinctive pattern of pruritic, flat-topped, erythematous papules which coalesce into an erythroderma-like eruption with classic sparing of the skin folds. Although the pathogenesis of this condition is incompletely understood, previous reports have suggested a notable link between PEO and various forms of malignancy and immunocompromised states. Here, we report a case of a healthy young male with no comorbidities who presented with the classical features of PEO that responded well to combination therapy comprised of topical corticosteroids and phototherapy.
小藤氏丘疹性红皮病(PEO)是一种罕见的皮肤疾病,其特征为独特的瘙痒性、平顶、红斑性丘疹,这些丘疹融合成类似红皮病的皮疹,皮肤褶皱处典型性不累及。尽管这种疾病的发病机制尚未完全明确,但既往报告提示PEO与多种形式的恶性肿瘤及免疫功能低下状态之间存在显著关联。在此,我们报告一例无合并症的健康年轻男性病例,该患者表现出PEO的典型特征,对局部糖皮质激素和光疗联合治疗反应良好。