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尼日利亚中北部一家耳鼻喉科诊所就诊患者的感音神经性听力损失分析。

Analysis of sensorineural hearing loss in patients attending an otolaryngology clinic in North Central Nigeria.

作者信息

Ma'an Nuhu D, Turaki Ishaku, Shwe David, Nansak Bulus, Babson Benjamin, Gomerep Simji, Malaya Lauren, Moffatt David, Shakibai Nasim, Paessler Slobodan, Makishima Tomoko, Shehu Nathan Y

机构信息

Otolaryngology Head and Neck Surgery Department of the Jos University Teaching Hospital, Plateau State, Nigeria.

Pediatrics Department of the Jos University Teaching Hospital, Plateau State, Nigeria.

出版信息

PLOS Glob Public Health. 2023 Apr 25;3(4):e0000685. doi: 10.1371/journal.pgph.0000685. eCollection 2023.

Abstract

Hearing loss is the third leading cause of years lived with disability. Approximately 1.4 billion people have hearing loss, of which 80% reside in low- and middle-income countries with limited audiology and otolaryngology care available to them. The objective of this study was to estimate period prevalence of hearing loss and audiogram patterns of patients attending an otolaryngology clinic in North Central Nigeria. A 10-year retrospective cohort study was carried out analyzing 1507 patient records of pure tone audiograms of patients at the otolaryngology clinic at Jos University Teaching Hospital, Plateau State, Nigeria. Prevalence of hearing loss of moderate or higher grade increased significantly and steadily after age 60. Compared to other studies, there was a higher prevalence of overall sensorineural hearing loss (24-28% in our study compared to 1.7-8.4% globally) and higher proportions of the flat audiogram configuration among the younger age patients (40% in younger patients compared to 20% in patients older than 60 years). The higher prevalence of the flat audiogram configuration compared to other parts of the world may be suggestive of an etiology specific to this region, such as the endemic Lassa Fever and Lassa virus infection in addition to cytomegalovirus or other viral infections associated with hearing loss.

摘要

听力损失是导致失能生存年数的第三大主要原因。约14亿人患有听力损失,其中80%生活在低收入和中等收入国家,这些国家的听力学和耳鼻喉科护理服务有限。本研究的目的是估计尼日利亚中北部一家耳鼻喉科诊所患者的听力损失期间患病率和听力图模式。开展了一项为期10年的回顾性队列研究,分析了尼日利亚高原州乔斯大学教学医院耳鼻喉科诊所1507例患者的纯音听力图记录。60岁以后,中度或更高等级听力损失的患病率显著且稳步上升。与其他研究相比,总体感音神经性听力损失的患病率更高(我们的研究中为24%-28%,而全球为1.7%-8.4%),并且在较年轻患者中平坦型听力图配置的比例更高(年轻患者中为40%,60岁以上患者中为20%)。与世界其他地区相比,平坦型听力图配置的患病率较高,这可能表明该地区存在特定病因,如地方性拉沙热和拉沙病毒感染,以及巨细胞病毒或其他与听力损失相关的病毒感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/922b/10128921/9403f5a4e9e3/pgph.0000685.g001.jpg

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