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异常冠状动脉的治疗——采用单纯胸廓内动脉技术的外科血运重建术

Treatment of Anomalous Coronary Arteries-Surgical Revascularisation Using the Pure Internal Thoracic Artery Technique.

作者信息

James Ramon L, Das De Sudeep, Singh Avtaar Singh Sanjeet, Dreisbach John, Watkins Stuart, Al-Attar Nawwar

机构信息

Department of Cardiac Surgery, Golden Jubilee National Hospital, Glasgow G81 4DH, UK.

Department of Radiology, Golden Jubilee National Hospital, Glasgow G81 4DH, UK.

出版信息

J Cardiovasc Dev Dis. 2023 Apr 2;10(4):155. doi: 10.3390/jcdd10040155.

Abstract

OBJECTIVES

To evaluate the use of CABG utilising an isolated pedicled Right Internal Thoracic Artery (RITA) or Left Internal Thoracic Artery (LITA) or the Pure Internal Thoracic Artery (PITA) technique to treat anomalous aortic origin of coronary artery (AAOCA).

METHODS

A retrospective review of all patients at our institution over an 8-year period (2013-2021) who underwent surgery for AAOCA was performed. Data assessed included patient demographics, initial presentation, morphology of coronary anomaly, surgical procedure, cross-clamp time, cardiopulmonary bypass time, and long-term outcome.

RESULTS

A total of 14 patients underwent surgery, including 11 males (78.5%) with a median logistic EuroSCORE of 1.605 (IQR 1.34). The median age was 62.5 years (IQR 48.75). Presentation was angina (7 patients), acute coronary syndrome (5 patients), incidental findings in aortic valve pathology (2 patients). AAOCA morphology varied: RCA from left coronary sinus (6), RCA from left main stem (3), left coronary artery from the right coronary sinus (1), left main stem arising from right coronary sinus (2) and circumflex artery arising from the right coronary sinus (2). Overall, 7 patients had co-existing flow-limiting coronary artery disease. CABG was performed using either a pedicled skeletonized RITA, LITA or PITA technique. There was no perioperative mortality. Overall median follow-up time was 43 months. One patient presented with recurrent angina secondary to graft failure at 2 years and there were two non-cardiac-related deaths at 4 and 35 months.

CONCLUSION

The use of internal thoracic artery grafts can provide a durable treatment option in patients with anomalous coronary arteries. The potential risk of graft failure in patients with no flow-limiting disease should be very carefully considered. However, a proposed benefit of this technique is the use of a pedicle flow to increase the long-term patency. More consistent results are obtained when ischaemia can be demonstrated preoperatively.

摘要

目的

评估使用孤立带蒂右胸廓内动脉(RITA)或左胸廓内动脉(LITA)或单纯胸廓内动脉(PITA)技术进行冠状动脉旁路移植术(CABG)治疗冠状动脉异常起源于主动脉(AAOCA)的效果。

方法

对我院8年期间(2013 - 2021年)所有接受AAOCA手术的患者进行回顾性研究。评估的数据包括患者人口统计学资料、初始表现、冠状动脉异常形态、手术过程、主动脉阻断时间、体外循环时间和长期预后。

结果

共有14例患者接受手术,其中男性11例(78.5%),中位逻辑欧洲心脏手术风险评估系统(EuroSCORE)为1.605(四分位间距1.34)。中位年龄为62.5岁(四分位间距48.75)。表现为心绞痛(7例)、急性冠状动脉综合征(5例)、主动脉瓣病变中的偶然发现(2例)。AAOCA形态各异:右冠状动脉起源于左冠状动脉窦(6例)、右冠状动脉起源于左主干(3例)、左冠状动脉起源于右冠状动脉窦(1例)、左主干起源于右冠状动脉窦(2例)、回旋支动脉起源于右冠状动脉窦(2例)。总体而言,7例患者合并有限制血流的冠状动脉疾病。使用带蒂骨骼化RITA、LITA或PITA技术进行CABG。围手术期无死亡病例。总体中位随访时间为43个月。1例患者在2年时因移植血管失败出现复发性心绞痛,4个月和35个月时有2例非心脏相关死亡。

结论

胸廓内动脉移植可为冠状动脉异常患者提供持久的治疗选择。对于无血流限制疾病的患者,应非常谨慎地考虑移植血管失败的潜在风险。然而,该技术的一个潜在益处是利用蒂部血流增加长期通畅率。术前能证明存在缺血时可获得更一致的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d838/10144681/b693b7b1d00d/jcdd-10-00155-g001.jpg

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