Action against Hunger, C/Duque de Sevilla no. 3, 28002 Madrid, Spain.
EPINUT Research Group (Ref. 920325), Unit of Physical Anthropology, Department of Biodiversity, Ecology, Faculty of Biological Sciences, and Evolution, Complutense University of Madrid, 28040 Madrid, Spain.
Nutrients. 2023 Apr 19;15(8):1975. doi: 10.3390/nu15081975.
the aim of this study is to evaluate the effectiveness and coverage of a simplified protocol that is implemented in health centers (HCs) and health posts (HPs) for children who are suffering from severe acute malnutrition (SAM) in the humanitarian context of Diffa.
We conducted a non-randomized community-controlled trial. The control group received outpatient treatment for SAM, without medical complications, at HCs and HPs with the standard protocol of community management of acute malnutrition (CMAM). Meanwhile, with respect to the intervention group, the children with SAM received treatment at the HCs and HPs through a simplified protocol wherein the mid-upper arm circumference (MUAC) and the presence of edema were used as the admission criteria, and the children with SAM were administered doses of fixed ready-to-use therapeutic food (RUTF).
A total of 508 children, who were all under 5 years and had SAM, were admitted into the study. The cured proportion was 87.4% in the control group versus 96.6% in the intervention group ( value = 0.001). There was no difference between the groups in the length of stay, which was 35 days, but the intervention group used a lower quantity of RUTF-70 sachets versus 90 sachets, per child cured. Coverage increases were observed in both groups.
the simplified protocol used at the HCs and HPs did not result in worse recovery and resulted in fewer discharge errors compared to the standard protocol.
本研究旨在评估在迪法人道主义环境下,卫生中心(HCs)和卫生所(HPs)实施简化方案对患有严重急性营养不良(SAM)儿童的有效性和覆盖范围。
我们进行了一项非随机社区对照试验。对照组在 HCs 和 HPs 接受门诊治疗,无医疗并发症,采用社区管理急性营养不良(CMAM)标准方案。同时,对于干预组,患有 SAM 的儿童在 HCs 和 HPs 接受简化方案治疗,采用中上臂围(MUAC)和水肿存在作为入院标准,患有 SAM 的儿童给予固定剂量的即用型治疗食品(RUTF)。
共有 508 名年龄均在 5 岁以下且患有 SAM 的儿童入组研究。对照组的治愈率为 87.4%,而干预组为 96.6%( 值=0.001)。两组的住院时间没有差异,均为 35 天,但干预组每个治愈儿童使用的 RUTF 袋数较少,为 70 袋,而不是 90 袋。两组的覆盖率均有所增加。
与标准方案相比,HCs 和 HPs 使用的简化方案并未导致恢复情况恶化,也减少了出院错误。