Kwak Stephen, Fishman Elliot K
Johns Hopkins University, 1800 Orleans St, Baltimore, MD 21287, USA.
Radiol Case Rep. 2023 Apr 13;18(6):2229-2231. doi: 10.1016/j.radcr.2023.03.032. eCollection 2023 Jun.
Ectopic mediastinal parathyroid is a common cause of recurrent and persistent hyperparathyroidism. Patients with recurrent and persistent hyperparathyroidism have elevated parathyroid hormone, which results in bone, vascular, and soft tissue abnormalities. While CT and MRI can be used to investigate ectopic parathyroid tissue, nuclear medicine Technetium-99m Sestamibi scan is the preferred method of imaging with sensitivity of 80%-90% and specificity of nearly 90%. Once identified, ectopic mediastinal parathyroid is treated with surgical resection though less invasive methods have gained popularity. We present a case of a 62-year-old female with recurrent secondary hyperparathyroidism that was localized to an ectopic mediastinal parathyroid gland.
异位纵隔甲状旁腺是复发性和持续性甲状旁腺功能亢进的常见原因。患有复发性和持续性甲状旁腺功能亢进的患者甲状旁腺激素升高,这会导致骨骼、血管和软组织异常。虽然CT和MRI可用于检查异位甲状旁腺组织,但核医学锝-99m甲氧基异丁基异腈扫描是首选的成像方法,其灵敏度为80%-90%,特异性接近90%。一旦确定,异位纵隔甲状旁腺通过手术切除进行治疗,尽管侵入性较小的方法越来越受欢迎。我们报告一例62岁女性复发性继发性甲状旁腺功能亢进病例,其病变定位于异位纵隔甲状旁腺。