Alizadeh Mohammadreza, Ravindran Aishwarya, Chkheidze Rati, Goyal Gaurav, Hosseini Mahdie, Shobeiri Parnian, Shafieioun Arezoo, Khalafi Mohammad, Shahidi Ramin, Sotoudeh Houman, Singhal Aparna
Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Clinical Pathology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA.
Radiol Case Rep. 2023 Apr 17;18(6):2259-2263. doi: 10.1016/j.radcr.2023.03.034. eCollection 2023 Jun.
Anaplastic lymphoma kinase (ALK)-positive histiocytosis is an uncommon condition, recently considered a separate condition from other histiocytosis by WHO 5th edition. It can involve intracranial structures. This manuscript describes a case of ALK-positive histiocytosis of the cavernous sinus, focusing on the radiologic and pathologic presentation of the entity. Our case had MRI manifestations mimicking meningioma, metastasis, and Langerhans histiocytosis. On CT imaging, benign osseous remodeling of the cavernous sinus was detected, which can be helpful in differentiating it from more common meningioma.
间变性淋巴瘤激酶(ALK)阳性组织细胞增多症是一种罕见疾病,世界卫生组织第5版最近将其视为与其他组织细胞增多症不同的独立病症。它可累及颅内结构。本文描述了一例海绵窦ALK阳性组织细胞增多症病例,重点关注该病症的放射学和病理学表现。我们的病例具有类似脑膜瘤、转移瘤和朗格汉斯组织细胞增多症的MRI表现。在CT成像上,检测到海绵窦的良性骨质重塑,这有助于将其与更常见的脑膜瘤相鉴别。