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一种简化的通用颈动脉支架置入方法。

A Simplified One-Size-Fits-All Approach to Carotid Stenting.

作者信息

Lahlouh Amro, Kiwan Ruba, Mandzia Jennifer, Pandey Sachin

机构信息

London Health Sciences Centre, Western University, Department of Clinical Neurological Sciences Center, London, Canada.

Department of Medical Imaging, Health Sciences North, Northern Ontario School of Medicine Sudbury, Sudbury, Canada.

出版信息

Can J Neurol Sci. 2024 Mar;51(2):220-225. doi: 10.1017/cjn.2023.48. Epub 2023 May 2.

Abstract

BACKGROUND

Carotid artery stenosis causes up to 20% of ischemic strokes. Stenting is used as an alternative to endarterectomy in symptomatic patients. Each commercially available stent offers numerous stent diameters/lengths. Most centers thus carefully match each individual stenosis to a specific stent length/diameter stent size. However, this process can be time-consuming and costly while the relative benefit of a custom stent sizing versus one-size-fits-all approach has not been well evaluated yet. We hypothesized that a 'one-size-fits-all' default approach to carotid stenting results in comparable results to a customized approach.

METHODS

We conducted a descriptive retrospective cohort study on 154 patients who presented to our academic carotid revascularization clinic with symptomatic carotid artery stenosis who underwent carotid artery stenting for peri- and postprocedural carotid artery stenting complications. The primary outcomes were periprocedural (within 24 hours of the procedure) or postprocedural (within 30 days of the procedure) TIA, stroke, or death. The secondary outcome was the estimated degree of stenosis on follow-up ultrasound performed within 6 months of the procedure.

RESULTS

The complication rate within the first 24 hours was 4.5% while that during the first 30 days postprocedure was 6.5%. Age over 80 and degree of stenosis on postprocedural cerebral angiogram were associated with an increased risk of complications. Severe restenosis was reported in 16.8% of patients within 6 months postprocedure.

CONCLUSION

Our study suggests that using a simplified, one-size-fits-all, approach to carotid stenting results in safe and effective outcomes, suggesting an alternative to simplify a complex medical procedure.

摘要

背景

颈动脉狭窄导致的缺血性中风占比高达20%。对于有症状的患者,支架置入术可作为动脉内膜切除术的替代方案。每种市售支架都有多种支架直径/长度可供选择。因此,大多数中心会仔细将每个个体的狭窄情况与特定的支架长度/直径尺寸相匹配。然而,这一过程可能既耗时又昂贵,而定制支架尺寸与一刀切方法的相对益处尚未得到充分评估。我们假设,颈动脉支架置入术采用“一刀切”的默认方法可产生与定制方法相当的结果。

方法

我们对154例因有症状的颈动脉狭窄到我们学术性颈动脉血运重建诊所就诊并接受颈动脉支架置入术以处理围手术期和术后颈动脉支架置入并发症的患者进行了描述性回顾性队列研究。主要结局为围手术期(手术24小时内)或术后(手术30天内)短暂性脑缺血发作(TIA)、中风或死亡。次要结局为术后6个月内进行的随访超声检查所估计的狭窄程度。

结果

术后24小时内的并发症发生率为4.5%,而术后30天内的并发症发生率为6.5%。年龄超过80岁以及术后脑血管造影的狭窄程度与并发症风险增加相关。术后6个月内,16.8%的患者报告出现严重再狭窄。

结论

我们的研究表明,采用简化的、一刀切的方法进行颈动脉支架置入术可产生安全有效的结果,这为简化复杂的医疗程序提供了一种替代方案。

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