Curraj Edwin, Gonzalez Rodriguez Elena
Centre interdisciplinaire des maladies osseuses (CiMO), Service de rhumatologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Université de Lausanne, 1011 Lausanne.
Rev Med Suisse. 2023 Apr 19;19(823):746-751. doi: 10.53738/REVMED.2023.19.823.746.
Despite the effectiveness of osteoporosis treatments, fear of side effects reduces both their prescription by doctors, and their acceptance by patients. The most common side effects are benign and transient, such as flu-like symptoms after zoledronate infusion, or nausea and dizziness after teriparatide introduction. On the other hand, the dreaded osteonecrosis of the jaw is very rare and associated with known risk factors. Only vertebral fractures after stopping denosumab make this treatment a matter for experienced practitioners. Therefore, knowing the side effects of prescribed treatments and explaining them to patients is essential to promote adherence.
尽管骨质疏松症治疗方法有效，但对副作用的担忧降低了医生的处方率以及患者的接受度。最常见的副作用是良性且短暂的，比如唑来膦酸输注后出现类似流感的症状，或特立帕肽使用后出现恶心和头晕。另一方面，令人恐惧的颌骨坏死非常罕见，且与已知风险因素相关。只有停用狄诺塞麦后出现椎体骨折，才使得这种治疗成为经验丰富的从业者需要考虑的问题。因此，了解所开治疗方法的副作用并向患者解释，对于提高依从性至关重要。
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