Gabal M A
Mycopathologia. 1986 Mar;93(3):163-8. doi: 10.1007/BF00443519.
A study on the use of thiabendazole in the treatment of bovine dermatophytosis caused by Trichophyton verrucosum was conducted. Fifteen infected animals were included in the study. Ten animals were treated with a thiabendazole-DMSO-salicylic acid mixture and 5 animals were left untreated as controls. The thiabendazole mixture was used topically on the skin lesions. Lesions resolved after 12 applications and 80% of the treated animals proved negative on mycological examination. All lesions healed completely after 16 applications. Thiabendazole proved to be fungicidal on specimens of skin scrapings infected with the arthroconidia and mycelial elements of the dermatophyte. The killing effect was achieved using dilutions of 1:10 000 and 1:20 000 at 4 and 7 days, respectively.
开展了一项关于使用噻苯达唑治疗由疣状毛癣菌引起的牛皮肤癣菌病的研究。该研究纳入了15只受感染动物。其中10只动物用噻苯达唑-二甲基亚砜-水杨酸混合物进行治疗，5只动物未接受治疗作为对照。噻苯达唑混合物局部用于皮肤病变处。在进行12次用药后病变消退，80%的治疗动物在真菌学检查中结果呈阴性。在进行16次用药后所有病变完全愈合。噻苯达唑对感染皮肤癣菌关节分生孢子和菌丝成分的皮肤刮屑标本具有杀真菌作用。分别在4天和7天时使用1:10000和1:20000的稀释液可达到杀灭效果。
