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在全球造影剂短缺期间诊断急性腹痛:单中心经验。

Diagnosing the acute abdomen during a global contrast shortage: a single centre experience.

机构信息

General Surgery, Royal Perth Hospital, Perth, Western Australia, Australia.

The University of Western Australia, Crawley, Western Australia, Australia.

出版信息

ANZ J Surg. 2023 Jun;93(6):1599-1603. doi: 10.1111/ans.18463. Epub 2023 May 3.

Abstract

BACKGROUND

The COVID-19 pandemic led to a global shortage of iodinated contrast media (ICM) in early 2022. ICM is used in more than half of the computed tomography of the abdomen and pelvis (CTAP) performed to diagnose an acute abdomen (AA). In response to the shortage, the RANZCR published contrast-conserving recommendations. This study aimed to compare AA diagnostic outcomes of non-contrast CTs performed before and during the shortage.

METHODS

A single-centre retrospective observational cohort study of all adult patients presenting with an AA who underwent a CTAP was conducted during the contrast shortage period from May to July 2022. The pre-shortage control comparison group was from January to March 2022; key demographics, imaging modality indication and diagnostic outcomes were collected and analysed using SPSS v27.

RESULTS

Nine hundred and sixty-two cases met the inclusion criteria, of which n = 502, 52.2% were in the shortage period group. There was a significant increase of 464% in the number of non-contrast CTAPs performed during the shortage period (P < 0.001). For the six AA pathologies, only n = 3, 1.8% of non-contrast CTAPs had equivocal findings requiring further imaging with a contrast CTAP. Of the total CTs performed, n = 464, 48.2% were negative.

CONCLUSION

This study showed that when non-contrast CTs are selected appropriately, they appear to be non-inferior to contrast-enhanced CTAPs in diagnosing acute appendicitis, colitis, diverticulitis, hernia, collection, and obstruction. This study highlights the need for further research into utilizing non-contrast scans for assessing the AA to minimize contrast-associated complications.

摘要

背景

2022 年初,COVID-19 大流行导致全球碘化对比剂(ICM)短缺。在一半以上用于诊断急腹症(AA)的腹部和骨盆计算机断层扫描(CTAP)中使用 ICM。为应对短缺,RANZCR 发布了节约对比剂的建议。本研究旨在比较短缺期间和之前进行的非对比 CT 对 AA 诊断结果的影响。

方法

对 2022 年 5 月至 7 月期间因 AA 接受 CTAP 的所有成年患者进行了一项单中心回顾性观察队列研究。短缺期的对照比较组为 2022 年 1 月至 3 月;使用 SPSS v27 收集和分析关键人口统计学、成像方式指征和诊断结果。

结果

符合纳入标准的有 962 例,其中 n=502,52.2%在短缺期组。短缺期非对比 CTAP 的数量显著增加了 464%(P<0.001)。对于六种 AA 病理,只有 n=3,1.8%的非对比 CTAP 结果不确定,需要进一步进行对比增强 CTAP 检查。在总共进行的 CT 中,n=464,48.2%为阴性。

结论

本研究表明,当适当选择非对比 CT 时,它们在诊断急性阑尾炎、结肠炎、憩室炎、疝、积聚和梗阻方面似乎与对比增强 CTAP 无差异。本研究强调需要进一步研究利用非对比扫描来评估 AA,以尽量减少与对比剂相关的并发症。

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