Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina, U.S.A.
J Clin Neurophysiol. 2023 May 1;40(4):378-381. doi: 10.1097/WNP.0000000000000905. Epub 2021 Oct 22.
Previous ultrasonographic studies of individuals with chronic inflammatory demyelinating polyneuropathy (CIDP) have shown nerve enlargement at several sites. This prospective study compares only the bilateral median and ulnar nerves of individuals with CIDP with reference values to determine the clinical usefulness of this focused approach as a diagnostic tool.
The cross-sectional area, echogenicity, and vascularity of the bilateral median and ulnar nerves of 25 subjects with CIDP were measured using ultrasound. Nineteen had typical CIDP based on the European Federation of Neurological Societies and the Peripheral Nerve Society guidelines, whereas six had atypical CIDP and were diagnosed based on clinical impression.
Focal nerve enlargement was found in at least one segment in all subjects. Subjects with typical CIDP had larger cross-sectional areas compared with subjects with atypical CIDP.
A focused ultrasound study, involving only the median and ulnar nerves, is sensitive for the detection of nerve enlargement in CIDP. Measuring the cross-sectional area of the median and ulnar nerves is clinically feasible and may help establish the diagnosis of CIDP.
先前针对慢性炎症性脱髓鞘性多发性神经病（CIDP）患者的超声研究表明，多个部位的神经增大。本前瞻性研究仅比较了 CIDP 个体双侧正中神经和尺神经与参考值，以确定这种集中方法作为诊断工具的临床实用性。
使用超声测量 25 例 CIDP 患者双侧正中神经和尺神经的横截面积、回声和血管。19 例基于欧洲神经病学会联合会和周围神经学会指南具有典型 CIDP，而 6 例具有不典型 CIDP，基于临床印象诊断。
所有患者至少在一个节段发现局灶性神经增大。与不典型 CIDP 患者相比，典型 CIDP 患者的横截面积更大。
仅涉及正中神经和尺神经的集中超声研究对 CIDP 患者神经增大的检测具有敏感性。测量正中神经和尺神经的横截面积在临床上是可行的，并且可能有助于确立 CIDP 的诊断。
Zotero 插件