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用于颅内动脉瘤栓塞的低记忆形状线圈:i-ED 线圈的初始及单中心经验

Low-memory shape coils for intracranial aneurysm coiling: Initial and single-center experience with the i-ED coil.

作者信息

Bazil Maximilian Jeremy, Fifi Johanna T, Yaeger Kurt A, Leacy Reade A De, Kellner Christopher Paul, Shigematsu Tomoyoshi

机构信息

Department of Neurological Surgery, Mount Sinai Hospital, New York City, United States.

Department of Neurological Surgery, Mount Sinai Health System, New York City, United States.

出版信息

Surg Neurol Int. 2023 Apr 21;14:142. doi: 10.25259/SNI_1116_2022. eCollection 2023.

Abstract

BACKGROUND

Endovascular aneurysmal coiling is a preventative alternative to clipping to avoid aneurysmal rupture. In the literature and our own experience, some common coiling challenges which arise include: (1) microcatheter kickback, (2) detachment zone rigidity, (3) intrasaccular compartmentalization of coils on deployment, and (4) attainability of high-density and effective packing with as few coils as possible.

METHODS

We retrospectively reviewed a consecutive case series of 15 intracranial aneurysm patients who received Kaneka i-ED Coils since their initial use in our practice (December 2020) till May 2022.

RESULTS

Of the 14 saccular aneurysm patients treated with i-ED coils, 2/14 (14.3%) achieved a Raymond-Roy (RR) score of 3A (internal remnant), 4/14 (28.6%) achieved RR 2 (slight neck remnant) and 8/14 (57.1%) achieved RR 1. One MoyaMoya patient (5.9%) with a fusiform aneurysm also achieved a complete occlusion by parent artery takedown in this series. Aneurysm volumes ranged from 8.15 mm 3 to 315.5 mm 3 with an average packing density of 36.23% and a standard deviation 8.87%. At 30 days, most of our cohort scored a 0 on the modified Rankin scale (mRS) (11/15), with two patients scoring at an mRS score of 1, one at an mRS score of 4, and one at an mRS score of 6. Low-memory shape, coil cases achieved a significantly higher packing density ( < 0.01) and PD/Coils-used ratio ( < 0.05) than other cases in our practice.

CONCLUSION

Our initial experience with i-ED coils has shown that they are a feasible strategy in a number of differently sized and shaped aneurysms. While fewer coils overall were not a statistically significant finding in this study, the future studies with larger cohorts are necessary and in progress.

摘要

背景

血管内动脉瘤栓塞术是一种替代夹闭术的预防方法,可避免动脉瘤破裂。在文献及我们自己的经验中,出现的一些常见栓塞挑战包括:(1)微导管回弹,(2)分离区僵硬,(3)弹簧圈在瘤腔内展开时出现分隔,以及(4)以尽可能少的弹簧圈实现高密度和有效填充。

方法

我们回顾性分析了自2020年12月在我院首次使用Kaneka i-ED弹簧圈至2022年5月期间连续收治的15例颅内动脉瘤患者的病例系列。

结果

在14例接受i-ED弹簧圈治疗的囊状动脉瘤患者中,2/14(14.3%)达到雷蒙德-罗伊(RR)3A级(内部残余),4/14(28.6%)达到RR 2级(轻微颈部残余),8/14(57.1%)达到RR 1级。本系列中1例患有梭形动脉瘤的烟雾病患者(5.9%)也通过闭塞载瘤动脉实现了完全闭塞。动脉瘤体积从8.15立方毫米至315.5立方毫米不等,平均填充密度为36.23%,标准差为8.87%。30天时,我们队列中的大多数患者改良Rankin量表(mRS)评分为0(11/15),2例患者评分为1,1例评分为4,1例评分为6。在我们的实践中,低记忆形状的弹簧圈病例的填充密度(<0.01)和PD/使用弹簧圈比例(<0.05)显著高于其他病例。

结论

我们对i-ED弹簧圈的初步经验表明,它们在多种不同大小和形状的动脉瘤中是一种可行的策略。虽然本研究中总体使用弹簧圈数量较少这一结果无统计学意义,但有必要且正在进行更大样本量的未来研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01c1/10159320/b0f6426e8d04/SNI-14-142-g001.jpg

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