Guérin J C, Martinat Y, Boniface E, Champel F
Rev Pneumol Clin. 1986;42(1):21-5.
It is classically admitted that young subjects with bullous dystrophy may develop lung cancer, but this rarely occurs. We report the case of 2 patients under 40 years of age who were found to have bronchial carcinoma. In such cases the clinical signs are not different from those of ordinary bronchial cancer, but the lesions are very often located in the upper lobes, adenocarcinoma is rare in contrast with the usual cancers on scars, the histological diagnosis is difficult and the prognosis usually poor owing to frequent extension to the chest wall. The problem of cancer on bullous dystrophy is essentially that of management of the dystrophy in young subjects: systematic surgery or wait-and-see attitude?
传统观点认为,患有大疱性营养不良的年轻患者可能会罹患肺癌,但这种情况很少发生。我们报告了2例40岁以下被发现患有支气管癌的患者。在这种情况下,临床症状与普通支气管癌并无不同,但病变常常位于上叶,与常见的瘢痕癌相比,腺癌较为少见,组织学诊断困难,且由于经常侵犯胸壁,预后通常较差。大疱性营养不良患者的癌症问题本质上是年轻患者营养不良的处理问题:是进行系统性手术还是采取观望态度?